{
  "abstract": "Issue: Despite major advances in HIV treatment and prevention, public health systems face persistent gaps in translating effective interventions into population-level impact. In Italy, 2,379 new HIV diagnoses were reported in 2024 (4/100.000), with mostly sexual transmission and a high proportion of late diagnosis. Late diagnosis reflects clinical delay and organizational and social barriers. Ensuring fair access to testing, prevention and care is then a public health priority across European settings.\n\nDescription: This work presents a public health framework developed in Italy (2023-2026) focusing on three pillars: combined prevention, professional training and system sustainability. It combines epidemiological data, European standards (ECDC/EACS) and recent policy changes. This approach aims to: reduce late diagnosis; improve access to testing and PrEP; strengthen adherence, retention, and re-engagement; ensure sustainable, integrated service delivery across settings.\n\nResults: Evidence shows that combined prevention improves early diagnosis and reduces transmission. However, in Italy and Europe, late diagnosis is still high (48-54% of new diagnoses). Thus introduction of reimbursed PrEP and long-acting prevention expands opportunities but requires new organizational models. Multidisciplinary interventions are associated with improved adherence (OR≈2.7) and viral suppression (OR≈4.1), although evidence quality is moderate.\n\nLessons: Effective HIV control needs to shift from isolated interventions to integrated, person-centred systems. Key actions include expanding testing in clinical and community settings and also PrEP access, strengthening multiprofessional training and remodeling care pathways to improve retention and re-engagement. Sustainability should be reframed from cost containment to value generation through early diagnosis, prevention and continuity of care. These lessons are transferable to other European countries facing similar challenges.\n\nKey messages: • Effective HIV tools exist, but impact depends on fair access and integrated delivery systems.\n\n• Reducing late diagnosis and improving retention are the key to a sustainable HIV control.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "abstract",
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "name": "CE Angelone"
    },
    {
      "name": "V Brescia"
    },
    {
      "name": "P Marraffa"
    },
    {
      "name": "G Orofino"
    },
    {
      "name": "G Cossu"
    },
    {
      "name": "M Carta"
    },
    {
      "name": "G Lo Moro"
    },
    {
      "name": "G Scaioli"
    },
    {
      "name": "R Siliquini"
    },
    {
      "name": "F Bert"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5pr6dpvwh67yx.bib",
  "cited_by": 0,
  "doi": "10.1093/eurpub/ckag169.566",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13698570/",
  "id": "5pr6dpvwh67yx",
  "issns": [
    "1101-1262",
    "1464-360X"
  ],
  "landing_url": "https://doi.org/10.1093/eurpub/ckag169.566",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "3. PARALLEL PROGRAMME"
    ],
    [
      "heading",
      "AcademicSubjects/MED00860"
    ],
    [
      "heading",
      "AcademicSubjects/SOC01210"
    ],
    [
      "heading",
      "AcademicSubjects/SOC02610"
    ],
    [
      "heading",
      "K.10. Pitch presentations: Prevention and equity in infectious disease control"
    ],
    [
      "openalex",
      "2725|HIV/AIDS Research and Interventions"
    ]
  ],
  "openalex": "W7223684231",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13698570/pdf/?tool=EBI",
  "pmcid": "PMC13698570",
  "pmid": null,
  "published": "2026-10-01",
  "publisher": "Oxford University Press",
  "ris": "https://research.draconitic.com/paper/5pr6dpvwh67yx.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:26Z",
      "native_id": "PMC13698570",
      "source": "pmc",
      "url": "https://doi.org/10.1093/eurpub/ckag169.566"
    },
    {
      "first_seen": "2026-10-30T12:21:45Z",
      "native_id": "PMC:PMC13698570",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13698570"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2725|HIV/AIDS Research and Interventions",
      "subfield": "infectious-disease"
    }
  ],
  "title": "Public health perspective on HIV prevention and care in Italy: from innovation to system impact",
  "title_text": "Public health perspective on HIV prevention and care in Italy: from innovation to system impact",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:35:25Z",
  "url": "https://research.draconitic.com/paper/5pr6dpvwh67yx",
  "venue": "The European Journal of Public Health",
  "versions": []
}