{
  "abstract": "Objective: To investigate the association between triglyceride-glucose index to waist-to-height ratio (TyG-WHtR) and nocturnal hypertension in metabolic syndrome (MetS) patients.\n\nMethods: This cross-sectional study included 180 adults with MetS undergoing 24-hour ambulatory blood pressure monitoring. Nocturnal hypertension was defined as mean nighttime SBP ≥120 mmHg and/or DBP ≥70 mmHg. Multivariable logistic regression and ROC analysis were performed.\n\nResults: Nocturnal hypertension was present in 48.3% of participants. TyG-WHtR was significantly higher in the nocturnal hypertension group (5.7 ± 0.5 vs. 5.1 ± 0.4, p = 6.05×10 ⁻¹³ ). After adjustment for confounders, TyG-WHtR remained independently associated with nocturnal hypertension (OR: 17.27, 95% CI: 5.76–58.87, p = 1.35×10 ⁻⁶ ). The AUC was 0.794 (95% CI: 0.73–0.86), with optimal cutoff 5.65 (sensitivity 56.3%, specificity 91.4%).\n\nConclusions: TyG-WHtR was independently associated with nocturnal hypertension in MetS patients and showed acceptable discriminative ability, significantly better than the TyG index alone.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Cardiology, The Third Affiliated Hospital of Chongqing Medical University"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Yanqiu Li"
    },
    {
      "affs": [
        0
      ],
      "name": "Hailong Su"
    },
    {
      "affs": [
        0
      ],
      "name": "Duan Wang"
    },
    {
      "affs": [
        0
      ],
      "name": "Xinlian Duan"
    },
    {
      "affs": [
        0
      ],
      "name": "Qin Zhang"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5syepmdwx57jx.bib",
  "cited_by": 0,
  "doi": "10.3389/fcvm.2026.1941261",
  "fulltext_url": null,
  "id": "5syepmdwx57jx",
  "issns": [
    "2297-055X"
  ],
  "landing_url": "https://www.frontiersin.org/articles/10.3389/fcvm.2026.1941261/full",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-03",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/5syepmdwx57jx.ris",
  "sources": [
    {
      "first_seen": "2026-11-03T12:21:34Z",
      "native_id": "10.3389/fcvm.2026.1941261",
      "source": "crossref",
      "url": "https://www.frontiersin.org/articles/10.3389/fcvm.2026.1941261/full"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "issn:2297-055X",
      "subfield": "cardiovascular"
    }
  ],
  "title": "The TyG-WHtR index as a novel predictor of nocturnal hypertension in metabolic syndrome",
  "title_text": "The TyG-WHtR index as a novel predictor of nocturnal hypertension in metabolic syndrome",
  "type": "peer-reviewed",
  "updated_at": "2026-11-05T00:21:10Z",
  "url": "https://research.draconitic.com/paper/5syepmdwx57jx",
  "venue": "Frontiers in Cardiovascular Medicine",
  "versions": []
}