{
  "abstract": "Objectives: To report prevalence, severity and clinical and inflammatory correlates of Post-Traumatic Stress Disorder (PTSD) in patients with schizophrenia.\n\nMethods: This cross-sectional, observational study included adult outpatients with schizophrenia/schizophreniform disorder. Assessments included the Mini-International Neuropsychiatric Interview (MINI), Post-traumatic Stress Disorder Symptom Severity Scale-Revised, Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schizophrenia (CDSS), Global Assessment of Functioning Scale (GAF), and inflammatory markers (neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio, systemic immune-inflammation index: platelets × neutrophils)/lymphocytes). Analyses compared patients with (SCZ + PTSD) versus without PTSD (SCZ-PTSD) across demographic, clinical, and biological variables.\n\nResults: SCZ + PTSD had higher PANSS-total scores (80.7 ± 19.5 vs. 71.6 ± 17.1; p = 0.003), more comorbid depression (73.8% vs. 23.3%; p < .001), higher CDSS scores (9.5 ± 4.9 vs. 3.2 ± 4.1; p < .001), more frequent suicide attempts (40.5% vs. 23.0%; p = 0.05), lower GAF scores (39.8 ± 12.3 vs. 49.6 ± 12.3; p < .001) and more medical comorbidities (51.1% vs. 42.8%; p = .014). Inflammatory markers did not differ significantly between groups. Logistic regression analyses identified higher CDSS scores (OR = 1.25, 95% CI [1.15, 1.36], p < .001) and lower GAF scores (OR = 0.96, 95% CI [0.93, 0.99], p = .007) as significant correlates of PTSD (r2 = 0.22).\n\nConclusions: PTSD is common and clinically relevant in people with schizophrenia, underscoring the need for routine screening and targeted interventions in this population.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Psychiatry, José T. Borda Hospital, Argentina",
    "Argentine Association of Psychiatry (AAP), Buenos Aires, Argentina",
    "Argentine Association of Biological Psychiatry (AAPB), Buenos Aires, Argentina",
    "José T. Borda Hospital, Argentina",
    "University of Buenos Aires, Argentina",
    "National University of Tucuman, Argentina",
    "Department of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY, USA",
    "Department of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA",
    "Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin Berlin, Berlin, Germany",
    "German Center for Mental Health (DZPG), Partner Site Berlin, Berlin, Germany",
    "Einstein Center for Population Diversity (ECPD), Berlin, Germany",
    "Einstein Center for Youth Mental Health (ECYM), Berlin, Germany"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Julieta Ramirez",
      "orcid": "0000-0002-0535-628X"
    },
    {
      "affs": [
        3
      ],
      "name": "María Delfina Tavella",
      "orcid": "0009-0004-1629-6894"
    },
    {
      "affs": [
        3
      ],
      "name": "German Weisbrot"
    },
    {
      "affs": [
        3,
        4
      ],
      "name": "Ricardo Corral"
    },
    {
      "affs": [
        3
      ],
      "name": "Adrian Cabrera"
    },
    {
      "affs": [
        5
      ],
      "name": "Alejo Corrales"
    },
    {
      "affs": [
        3
      ],
      "name": "José Gramajo"
    },
    {
      "affs": [
        3
      ],
      "name": "Nora Crespi"
    },
    {
      "affs": [
        6,
        7,
        8,
        9,
        10,
        11
      ],
      "name": "Christoph U. Correll",
      "orcid": "0000-0002-7254-5646"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5vxw242tk691t.bib",
  "cited_by": 0,
  "doi": "10.1017/s1092852926101035",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13732599/",
  "id": "5vxw242tk691t",
  "issns": [
    "1092-8529",
    "2165-6509"
  ],
  "landing_url": "https://doi.org/10.1017/s1092852926101035",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Original Research"
    ],
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      "openalex",
      "3203|Posttraumatic Stress Disorder Research"
    ]
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  "openalex": "W7165031787",
  "pdf_url": "https://www.cambridge.org/core/services/aop-cambridge-core/content/view/452A9746D58996DFCE2C3DFB417F681B/S1092852926101035a.pdf/div-class-title-prevalence-severity-and-correlates-of-post-traumatic-stress-disorder-in-205-outpatients-with-schizophrenia-results-from-a-cross-sectional-observational-study-assessing-diagnoses-via-the-mini-international-neuropsychiatric-interview-div.pdf",
  "pmcid": "PMC13732599",
  "pmid": "42305031",
  "published": "2026-06-17",
  "publisher": "Cambridge University Press",
  "ris": "https://research.draconitic.com/paper/5vxw242tk691t.ris",
  "sources": [
    {
      "first_seen": "2026-11-08T12:22:34Z",
      "native_id": "PMC13732599",
      "source": "pmc",
      "url": "https://doi.org/10.1017/s1092852926101035"
    }
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  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:3203|Posttraumatic Stress Disorder Research",
      "subfield": "psychiatry"
    }
  ],
  "title": "Prevalence, severity, and correlates of post-traumatic stress disorder in 205 outpatients with schizophrenia: results from a cross-sectional, observational study assessing diagnoses via the Mini-International Neuropsychiatric Interview",
  "title_text": "Prevalence, severity, and correlates of post-traumatic stress disorder in 205 outpatients with schizophrenia: results from a cross-sectional, observational study assessing diagnoses via the Mini-International Neuropsychiatric Interview",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T12:22:34Z",
  "url": "https://research.draconitic.com/paper/5vxw242tk691t",
  "venue": "CNS Spectrums",
  "versions": []
}