{
  "abstract": "Inspired by a study reporting on the zinc oxide-induced mechanochemical conglomerate formation of racemic amino acids, we investigated the reaction behavior of the analogous 19F-labeled DL-valine. Solid-state NMR spectroscopy under magic-angle spinning (MAS) conditions was employed as the central analytical technique to analyze the reaction products. In contrast to our expectation, no conglomerate formation occurred, and in the presence of ZnO and methanol a polymeric complex with one zinc and two fluorinated valine molecules was formed in a vibrational ball mill. Repeating these experiments with non-fluorinated valine led to a rather unusual and unique tetranuclear species with an overall composition of Zn4(D-Val)4(L-Val)4 as determined by single-crystal analysis and solid-state NMR. The latter complex was also formed when an equimolar ratio of the two enantiopure valine phases was combined in the ball mill with ZnO and methanol. The use of Resonant Acoustic Mixing (RAM) led to the same complex, but the efficiency of its formation varied significantly depending on the reaction conditions.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 13,
  "authors": [
    {
      "name": "Sven Moos"
    },
    {
      "name": "Pascal Trommelschläger"
    },
    {
      "name": "Tobias Krückel"
    },
    {
      "name": "Calogero Quaranta"
    },
    {
      "name": "Niklas Aengenvoort"
    },
    {
      "name": "Fabio Manzoni"
    },
    {
      "name": "Jas S. Ward"
    },
    {
      "name": "Kathrin Rübartsch"
    },
    {
      "name": "Mirijam Zobel"
    },
    {
      "name": "Manu Lahtinen"
    },
    {
      "name": "Kari Rissanen"
    },
    {
      "name": "Carsten Bolm",
      "orcid": "0000-0001-9415-9917"
    },
    {
      "name": "Thomas Wiegand"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5wd9zk8kjtc8d.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15009741/v1",
  "fulltext_url": null,
  "id": "5wd9zk8kjtc8d",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15009741/v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1606|Crystallography and molecular interactions"
    ]
  ],
  "openalex": "W7215064560",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15009741/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-01",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/5wd9zk8kjtc8d.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:21Z",
      "native_id": "10.26434/chemrxiv.15009741",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15009741/v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1606|Crystallography and molecular interactions",
      "subfield": "physical"
    }
  ],
  "title": "Mechanochemical conglomerate formation by ball milling - or not?",
  "title_text": "Mechanochemical conglomerate formation by ball milling - or not?",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:21Z",
  "url": "https://research.draconitic.com/paper/5wd9zk8kjtc8d",
  "venue": "ChemRxiv",
  "versions": []
}