{
  "abstract": "Objectives\n\nThis is a protocol for a Cochrane review (intervention). The objectives are as follows: To assess the comparative benefits and harms of systemic antibiotic regimens for the treatment of acute pelvic inflammatory disease in women of reproductive age. The secondary objectives are: to estimate the incremental effect of adding nitroimidazole to an antibiotic backbone; to compare the efficacy of azithromycin-containing regimens with relevant alternatives, where the evidence network permits (in Network B, this comparison depends on setting-disaggregated data from a single eligible trial and may not be estimable); and to describe narratively whether treatment hierarchies appear consistent between the outpatient (Network A) and inpatient (Network B) evidence, since direct statistical comparison between networks is not undertaken.",
  "abstract_shown": true,
  "affiliations": [
    "Second Department of Obstetrics and Gynecology, Aretaieio Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.",
    "Cochrane Athens, Athens, Greece.",
    "School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.",
    "School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, Scotland, UK.",
    "Assisted Reproduction Unit, Second Department of Obstetrics and Gynaecology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.",
    "Statistics, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.",
    "University of Birmingham, Birmingham, UK.",
    "Birmingham City University, Birmingham, UK.",
    "Ginecologia e Obstetricia, UFRGS-FAMED, Porto Alegre, Brazil."
  ],
  "article_type": "systematic review",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Michail Papapanou",
      "orcid": "0000-0001-8331-2402"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Melina Nikolakea",
      "orcid": "0000-0001-9095-0007"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Ismini Tsakiri",
      "orcid": "0000-0002-9490-9973"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Maria Toulaki",
      "orcid": "0009-0004-1822-6865"
    },
    {
      "affs": [
        1,
        3
      ],
      "name": "Kalliopi Syristatidi"
    },
    {
      "affs": [
        1,
        4
      ],
      "name": "Charalampos S Siristatidis",
      "orcid": "0000-0003-0850-6623"
    },
    {
      "affs": [
        5
      ],
      "name": "Patricia Ziegelmann",
      "orcid": "0000-0002-2851-2011"
    },
    {
      "affs": [
        6,
        7
      ],
      "name": "Jonathan Ross",
      "orcid": "0000-0002-4193-6919"
    },
    {
      "affs": [
        8
      ],
      "name": "Ricardo F Savaris",
      "orcid": "0000-0002-2779-5443"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5xebbzsdhhh66.bib",
  "cited_by": 0,
  "doi": "10.1002/14651858.cd016401",
  "fulltext_url": "https://europepmc.org/articles/PMC13685952",
  "id": "5xebbzsdhhh66",
  "issns": [
    "1469-493X"
  ],
  "landing_url": "https://europepmc.org/article/MED/42905124",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2404|Reproductive tract infections research"
    ]
  ],
  "openalex": "W7223141565",
  "pdf_url": "https://europepmc.org/articles/PMC13685952?pdf=render",
  "pmcid": "PMC13685952",
  "pmid": "42905124",
  "published": "2026-10-21",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/5xebbzsdhhh66.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:53Z",
      "native_id": "MED:42905124",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42905124"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2404|Reproductive tract infections research",
      "subfield": "microbiology"
    }
  ],
  "title": "Antibiotic therapy for pelvic inflammatory disease: a network meta-analysis.",
  "title_text": "Antibiotic therapy for pelvic inflammatory disease: a network meta-analysis.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:53Z",
  "url": "https://research.draconitic.com/paper/5xebbzsdhhh66",
  "venue": "The Cochrane database of systematic reviews",
  "versions": []
}