{
  "abstract": "Background\n\nAccidental extubation remains a significant clinical concern in airway management, particularly in emergency and anesthetic settings. While commercial tube holders have shown improved fixation stability over adhesive tape, cost and availability limit their use in many healthcare systems. This study introduces a newly developed Iranian endotracheal tube (ETT) holder, Persifix, and evaluates its mechanical performance relative to a commercial Locktite model and the conventional adhesive tape method.Methods\n\nA total of 170 controlled tests were conducted using a human airway manikin. Three fixation methods-adhesive tape, Persifix, and Locktite tube holders-were assessed under lateral and frontal force vectors using weights of 750 g and 1000 g. Displacement was measured in both depth and lateral dimensions under dynamic (tug) and static (non-tug) conditions. Statistical analysis was performed using Kruskal-Wallis and Mann-Whitney U tests, with Bonferroni's post hoc comparisons (α = 0.05).Results\n\nThe adhesive tape method demonstrated significantly greater displacement in depth across most test conditions (e.g., left side, 1000 g, no tug: 2.54 ± 3.63 mm vs. Persifix: 1.76 ± 1.78 mm, p = 0.032; Locktite: 0.53 ± 0.44 mm, p < 0.001). In frontal force tests with 1000 g and tug, the Persifix showed reduced displacement (0.41 ± 0.16 mm) compared to both adhesive tape (2.62 ± 4.25 mm, p = 0.001) and Locktite (0.52 ± 1.33 mm, p = 0.032). Lateral displacement in width was also significantly lower with both tube holders (e.g., 750 g with tug: Persifix 3.34 ± 5.20 mm vs. adhesive tape 3.16 ± 15.00 mm, p = 0.005). No statistically significant differences were observed between the Persifix and Locktite tube holders in most conditions (p > 0.05), indicating comparable fixation stability.Conclusion\n\nThe Iranian tube holder, Persifix, demonstrated statistically significant reductions in ETT displacement compared to adhesive tape across multiple force vectors and weight conditions. Its mechanical performance was comparable to the commercial Locktite model, suggesting its potential utility as a cost-effective and clinically reliable alternative for airway stabilization in resource-limited settings.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Emergency Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.",
    "Department of Emergency Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. m_nasr54@med.mui.ac.ir.",
    "Department of Health in Disasters and Emergencies, School of Management and Medical Informatics, Isfahan University of Medical Sciences, Isfahan, Iran. m_nasr54@med.mui.ac.ir."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Alireza Abootalebi Ghahnavieh",
      "orcid": "0000-0003-0775-2910"
    },
    {
      "affs": [
        0
      ],
      "name": "Mehran Haddadi"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Mehdi Nasr Isfahani",
      "orcid": "0000-0002-0236-6546"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/5z0jm25ycwgg5.bib",
  "cited_by": 0,
  "doi": "10.1186/s12871-026-04147-6",
  "fulltext_url": "https://europepmc.org/articles/PMC13721623",
  "id": "5z0jm25ycwgg5",
  "issns": [
    "1471-2253"
  ],
  "landing_url": "https://europepmc.org/article/MED/42958043",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research"
    ],
    [
      "openalex",
      "2703|Airway Management and Intubation Techniques"
    ]
  ],
  "openalex": "W7172204168",
  "pdf_url": "https://europepmc.org/articles/PMC13721623?pdf=render",
  "pmcid": "PMC13721623",
  "pmid": "42958043",
  "published": "2026-08-03",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/5z0jm25ycwgg5.ris",
  "sources": [
    {
      "first_seen": "2026-11-01T00:20:47Z",
      "native_id": "MED:42958043",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42958043"
    },
    {
      "first_seen": "2026-11-03T12:22:17Z",
      "native_id": "PMC13721623",
      "source": "pmc",
      "url": "https://doi.org/10.1186/s12871-026-04147-6"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2703|Airway Management and Intubation Techniques",
      "subfield": "surgery"
    }
  ],
  "title": "Mechanical stability of endotracheal tube fixation: a performance comparison between two tube holders and a conventional method.",
  "title_text": "Mechanical stability of endotracheal tube fixation: a performance comparison between two tube holders and a conventional method.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:22:17Z",
  "url": "https://research.draconitic.com/paper/5z0jm25ycwgg5",
  "venue": "BMC anesthesiology",
  "versions": []
}