{
  "abstract": "Hantavirus cardiopulmonary syndrome (HCPS) due to Andes virus (ANDV) is a fulminant yet potentially reversible cause of respiratory and circulatory failure requiring timely critical care. This article addresses eleven practical questions on ICU management, drawing on clinical experience and research from the Chilean healthcare system. The recommendations cover early recognition, diagnostic workup, haemodynamic monitoring, cautious fluid and vasoactive support, respiratory management, VA-ECMO referral, daily ICU care, recovery, common pitfalls, and therapies with limited evidence. Because no antiviral or immunomodulatory therapy has consistently improved outcomes, survival relies on early suspicion, physiology-guided supportive care, and rapid escalation to ECMO-capable centres when severe cardiopulmonary failure develops.",
  "abstract_shown": true,
  "affiliations": [
    "Departamento de Medicina Interna, Facultad de Medicina, Universidad de Concepción, Concepción, Chile",
    "Unidad de Cuidados Intensivos, Hospital Guillermo Grant Benavente, Concepción, Chile",
    "Departamento de Enfermedades Infecciosas e Inmunología Pediátricas, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile",
    "SENTINET: Surveillance, Epidemiology, and New Technologies for Infectious Emerging Threats, Santiago, Chile",
    "Departamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Avenida Diagonal Paraguay 362, Santiago, Chile",
    "Unisabana Center for Translational Science, School of Medicine, Universidad de La Sabana, Chia, Colombia",
    "Critical Care Department, Clínica Universidad de La Sabana, Chía, Colombia",
    "ISARIC, University of Oxford, Pandemic Sciences Institute, Oxford, UK",
    "The Latin American Intensive Care Research Network (LIVEN)"
  ],
  "article_type": "brief report",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Nicolás Pavez"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Paula Fernández"
    },
    {
      "affs": [
        2,
        3
      ],
      "name": "Marcela Ferrés"
    },
    {
      "affs": [
        4
      ],
      "name": "Jaime Retamal"
    },
    {
      "affs": [
        5,
        6,
        7,
        8
      ],
      "name": "Luis Felipe Reyes"
    },
    {
      "affs": [
        3,
        4,
        8
      ],
      "name": "Eduardo Kattan"
    },
    {
      "affs": [
        3,
        4,
        8
      ],
      "name": "Alejandro Bruhn"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/63ew3p51d9x6j.bib",
  "cited_by": 0,
  "doi": "10.1186/s13054-026-06233-0",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13737698/",
  "id": "63ew3p51d9x6j",
  "issns": [
    "1364-8535",
    "1466-609X"
  ],
  "landing_url": "https://doi.org/10.1186/s13054-026-06233-0",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Debate"
    ],
    [
      "openalex",
      "2725|Viral Infections and Vectors"
    ]
  ],
  "openalex": "W7202030543",
  "pdf_url": null,
  "pmcid": "PMC13737698",
  "pmid": "42983565",
  "published": "2026-08-09",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/63ew3p51d9x6j.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T12:22:49Z",
      "native_id": "PMC13737698",
      "source": "pmc",
      "url": "https://doi.org/10.1186/s13054-026-06233-0"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2725|Viral Infections and Vectors",
      "subfield": "infectious-disease"
    }
  ],
  "title": "Eleven questions on Hantavirus cardiopulmonary syndrome management in the ICU",
  "title_text": "Eleven questions on Hantavirus cardiopulmonary syndrome management in the ICU",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T12:22:49Z",
  "url": "https://research.draconitic.com/paper/63ew3p51d9x6j",
  "venue": "Critical Care",
  "versions": []
}