{
  "abstract": "A gas-free, one-pot synthesis of heterocyclic primary sulfonamides from heterocyclic thiols is described. This method employs sodium hypochlorite pentahydrate as a solid chlorinating source and aqueous ammonia as a nitrogen source, avoiding hazardous chlorine and ammonia gases. The protocol was applied to a range of pyrimidine, pyridine, benzothiazole, and tetrazole derivatives. The utility of this method was further demonstrated by 15N-labeling and multigram-scale synthesis.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "name": "Masahiro Abe"
    },
    {
      "name": "Misaki Furukawa"
    },
    {
      "name": "Minji Lee"
    },
    {
      "name": "Akiho Mizukami"
    },
    {
      "name": "Kiyofumi Inamoto"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/69cnv5w6agsae.bib",
  "cited_by": 0,
  "doi": "10.1248/cpb.c26-00250",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/cpb/74/7/74_c26-00250/_article",
  "id": "69cnv5w6agsae",
  "issns": [
    "1347-5223",
    "0009-2363"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/cpb/74/7/74_c26-00250/_article",
  "language": null,
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "chemistry/medicinal"
    ],
    [
      "openalex",
      "1605|Sulfur-Based Synthesis Techniques"
    ]
  ],
  "openalex": "W7170131029",
  "pdf_url": "https://www.jstage.jst.go.jp/article/cpb/74/7/74_c26-00250/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-24",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/69cnv5w6agsae.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:34Z",
      "native_id": "10.1248/cpb.c26-00250",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/cpb/74/7/74_c26-00250/_article"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Sulfur-Based Synthesis Techniques",
      "subfield": "organic"
    }
  ],
  "title": "Development of an Efficient Synthetic Method for Nitrogen-Containing Heterocyclic Primary Sulfonamides",
  "title_text": "Development of an Efficient Synthetic Method for Nitrogen-Containing Heterocyclic Primary Sulfonamides",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:34Z",
  "url": "https://research.draconitic.com/paper/69cnv5w6agsae",
  "venue": "Chemical and Pharmaceutical Bulletin",
  "versions": []
}