{
  "abstract": "Triphenylphosphine sulfide ligand (L1) exhibited excellent catalytic performance in the copper-catalyzed azide–alkyne cycloaddition (CuAAC) of ethynyldiphenylphosphine oxide (1) and azides (2), affording functionalized 4-phosphinyl-1,2,3-triazoles (3) in good yields. L1 showed superior performance to triphenylphosphine oxide, triphenylphosphine, and the sulfide ligands examined, possibly owing to suitable coordination of its P=S moiety to Cu. And, the products could be transformed to 4-phosphanyl-1,2,3-triazoles (4) and 1-benzyl-substituted 1,2,3-triazoles (5) by reduction and dephosphinylation, respectively. This [Cu]/L1-catalyzed protocol, the first example of the application of triphenylphosphine sulfide as a ligand in CuAAC, featured the following advantages: low catalyst loading, relatively short reaction time, broad functional group tolerance, high yields, and facile scalability.",
  "abstract_shown": true,
  "affiliations": [
    "State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China",
    "Department of Applied Chemistry, Okayama University of Science, 1-1 Ridai-cho, Kita-ku, Okayama 700-0005, Japan"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 12,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Jie Shen"
    },
    {
      "affs": [
        0
      ],
      "name": "Jinwei Li"
    },
    {
      "affs": [
        0
      ],
      "name": "Shitang Xu"
    },
    {
      "affs": [
        1
      ],
      "name": "Yasuhiro Okuda"
    },
    {
      "name": "Zetao Jiang"
    },
    {
      "affs": [
        0
      ],
      "name": "Bingting Yao"
    },
    {
      "affs": [
        0
      ],
      "name": "Hui Li"
    },
    {
      "name": "Yinchun Jiao"
    },
    {
      "name": "Zilong Tang"
    },
    {
      "name": "Lifen Peng"
    },
    {
      "affs": [
        1
      ],
      "name": "Akihiro Orita",
      "orcid": "0000-0001-8684-2951"
    },
    {
      "affs": [
        0
      ],
      "name": "Xinhua Xu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6ahp482p4wwfr.bib",
  "cited_by": 0,
  "doi": "10.3390/molecules31214005",
  "fulltext_url": null,
  "id": "6ahp482p4wwfr",
  "issns": [
    "1420-3049"
  ],
  "landing_url": "https://www.mdpi.com/1420-3049/31/21/4005",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-06",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/6ahp482p4wwfr.ris",
  "sources": [
    {
      "first_seen": "2026-11-06T12:21:01Z",
      "native_id": "10.3390/molecules31214005",
      "source": "crossref",
      "url": "https://www.mdpi.com/1420-3049/31/21/4005"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "issn:1420-3049",
      "subfield": "general"
    }
  ],
  "title": "Triphenylphosphine Sulfide as an Efficient Ligand in CuAAC to Synthesize 4-Phosphinyl-1,2,3-Triazoles",
  "title_text": "Triphenylphosphine Sulfide as an Efficient Ligand in CuAAC to Synthesize 4-Phosphinyl-1,2,3-Triazoles",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T00:21:58Z",
  "url": "https://research.draconitic.com/paper/6ahp482p4wwfr",
  "venue": "Molecules",
  "versions": []
}