{
  "abstract": "Plasmodium falciparum is the leading cause of severe malaria. The spleen plays a central role in the clearance of the infection in conjunction with antimalarial treatment. Splenectomized patients lack sufficient clearance functions. We report a case of severe P. falciparum infection with multi-organ involvement acquired in Uganda in a splenectomized patient with a persistently high parasitemia level despite appropriate antimalarial treatment. The case emphasizes the challenges associated with severe malaria in asplenic patients.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Clinical Microbiology, Odense University Hospital, J. B. Winsloews Vej 4, 5000, Odense C, Denmark. bolette.wittenberg@rsyd.dk.",
    "Department of Clinical Microbiology, Odense University Hospital, J. B. Winsloews Vej 4, 5000, Odense C, Denmark.",
    "Department of Clinical Microbiology, Aalborg University Hospital, Aalborg, Denmark.",
    "Department of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark.",
    "Center for Translational Medicine and Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.",
    "Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark.",
    "Clinical Center for Emerging and Vector Borne Infections, Department of Infectious Diseases, Odense University Hospital, Odense, Denmark."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Bolette Wittenberg"
    },
    {
      "affs": [
        1
      ],
      "name": "Gitte Nyvang Hartmeyer"
    },
    {
      "affs": [
        2
      ],
      "name": "David Fuglsang-Damgaard"
    },
    {
      "affs": [
        3
      ],
      "name": "Torsten Roed"
    },
    {
      "affs": [
        4,
        5
      ],
      "name": "Helle Hansson"
    },
    {
      "affs": [
        6
      ],
      "name": "Fredrikke Christie Knudtzen"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6ajjq6tw9w81q.bib",
  "cited_by": 0,
  "doi": "10.1186/s12936-026-06079-5",
  "fulltext_url": "https://europepmc.org/articles/PMC13689024",
  "id": "6ajjq6tw9w81q",
  "issns": [
    "1475-2875"
  ],
  "landing_url": "https://europepmc.org/article/MED/42919362",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RC109-216"
    ],
    [
      "lcc",
      "RC955-962"
    ],
    [
      "openalex",
      "2739|Malaria Research and Control"
    ]
  ],
  "openalex": "W7172290061",
  "pdf_url": "https://europepmc.org/articles/PMC13689024?pdf=render",
  "pmcid": "PMC13689024",
  "pmid": "42919362",
  "published": "2026-08-01",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/6ajjq6tw9w81q.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:02Z",
      "native_id": "MED:42919362",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42919362"
    },
    {
      "first_seen": "2026-10-30T13:45:34Z",
      "native_id": "78165e2f7e84403c8e8b16db791ae9bb",
      "source": "doaj",
      "url": "https://doi.org/10.1186/s12936-026-06079-5"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2739|Malaria Research and Control",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Severe Plasmodium falciparum infection with multi-organ involvement in an asplenic patient: a case report.",
  "title_text": "Severe Plasmodium falciparum infection with multi-organ involvement in an asplenic patient: a case report.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:45:34Z",
  "url": "https://research.draconitic.com/paper/6ajjq6tw9w81q",
  "venue": "Malaria journal",
  "versions": []
}