{
  "abstract": "Background: Lumen-apposing metal stent (LAMS) placement enables transmural drainage of walled-off necrosis (WON) with secure anchoring and provides endoscopic access for subsequent necrosectomy. This study compared the efficacy and safety of two commercially available LAMS designs (Hot-Axios vs. Micro-Tech) in patients with infected WON. Methods: We retrospectively reviewed patients with infected WON who underwent endoscopic ultrasound (EUS)-guided LAMS placement followed by endoscopic debridement at our center between August 2020 and June 2025. Results: Thirty-one patients were included (Hot-Axios, n = 21; Micro-Tech, n = 10). The overall necrosectomy success rate was 80.65% (25/31). Necrosectomy success was numerically higher with Hot-Axios than with Micro-Tech (85.71% vs. 70.00%), but the difference was not statistically significant (p = 0.358). There was a statistically significant difference in the incidence of complications between the two groups (P = 0.007); bleeding occurred more frequently in the Hot-Axios group (33.33% vs. 0%), whereas stent migration was more common in the Micro-Tech group (0% vs. 20.00%). Conclusions: In conclusion, endoscopic necrosectomy for infected WON using LAMS is feasible and effective. Hot-Axios may provide more secure fixation and better resistance to migration; however, it may carry a higher risk of bleeding.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Gastroenterology, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou, Zhejiang, China",
    "Key Laboratory of Integrated Traditional Chinese and Western Medicine for Biliary and Pancreatic Diseases of Zhejiang Province, Hangzhou, Zhejiang, China",
    "Hangzhou Institute of Digestive Diseases, Hangzhou, Zhejiang, China",
    "Zhejiang Provincial Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research, Hangzhou, Zhejiang, China",
    "Department of Gastroenterology, Olive View-UCLA Medical Center and David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America"
  ],
  "article_type": "Research Article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Cong Ding"
    },
    {
      "affs": [
        1
      ],
      "name": "Hui Wang"
    },
    {
      "affs": [
        2
      ],
      "name": "Yifeng Zhou"
    },
    {
      "affs": [
        3
      ],
      "name": "Jing Yang"
    },
    {
      "affs": [
        4
      ],
      "name": "Xia Wang"
    },
    {
      "name": "Goufan Shen"
    },
    {
      "name": "Xiaofeng Zhang"
    },
    {
      "name": "Richard Hu"
    },
    {
      "name": "Jianfeng Yang"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6an5ensaxe4jm.bib",
  "cited_by": 0,
  "doi": "10.1371/journal.pone.0361859",
  "fulltext_url": null,
  "id": "6an5ensaxe4jm",
  "issns": [
    "1932-6203"
  ],
  "landing_url": "https://doi.org/10.1371/journal.pone.0361859",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "plos",
      "/Medicine and health sciences/Clinical medicine/Signs and symptoms/Hemorrhage"
    ],
    [
      "plos",
      "/Medicine and health sciences/Clinical medicine/Signs and symptoms/Lesions"
    ],
    [
      "plos",
      "/Medicine and health sciences/Clinical medicine/Signs and symptoms/Necrosis"
    ],
    [
      "plos",
      "/Medicine and health sciences/Diagnostic medicine/Diagnostic radiology/Ultrasound imaging"
    ],
    [
      "plos",
      "/Medicine and health sciences/Gastroenterology and hepatology/Pancreatitis"
    ],
    [
      "plos",
      "/Medicine and health sciences/Radiology and imaging/Diagnostic radiology/Ultrasound imaging"
    ],
    [
      "plos",
      "/Medicine and health sciences/Surgical and invasive medical procedures/Endoscopy"
    ],
    [
      "plos",
      "/Medicine and health sciences/Surgical and invasive medical procedures/Endoscopy/Endoscopic surgery/Endoscopic plastic surgery"
    ],
    [
      "plos",
      "/Medicine and health sciences/Surgical and invasive medical procedures/Plastic surgery and reconstructive techniques/Endoscopic plastic surgery"
    ],
    [
      "plos",
      "/Medicine and health sciences/Surgical and invasive medical procedures/Stent implantation"
    ],
    [
      "plos",
      "/Medicine and health sciences/Vascular medicine/Hemorrhage"
    ],
    [
      "plos",
      "/Research and analysis methods/Imaging techniques/Diagnostic radiology/Ultrasound imaging"
    ]
  ],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-03",
  "publisher": "Public Library of Science",
  "ris": "https://research.draconitic.com/paper/6an5ensaxe4jm.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T12:20:43Z",
      "native_id": "10.1371/journal.pone.0361859",
      "source": "plos",
      "url": "https://doi.org/10.1371/journal.pone.0361859"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "plos:diagnostic radiology",
      "subfield": "imaging"
    },
    {
      "field": "medicine",
      "origin": "plos:surgical and invasive medical procedures",
      "subfield": "surgery"
    }
  ],
  "title": "Endoscopic necrosectomy of infected pancreatic Walled-Off Necrosis using two types of Lumen-Apposing Metal Stents",
  "title_text": "Endoscopic necrosectomy of infected pancreatic Walled-Off Necrosis using two types of Lumen-Apposing Metal Stents",
  "type": "peer-reviewed",
  "updated_at": "2026-11-05T12:20:11Z",
  "url": "https://research.draconitic.com/paper/6an5ensaxe4jm",
  "venue": "PLOS One",
  "versions": []
}