{
  "abstract": "We examined the impact of semaglutide treatment and discontinuation in a pre-clinical model for binge eating. Treatment reduced body weight and palatable food intake in mice with binge-like eating. Discontinuation reinstated binge-like eating and caused body weight to significantly exceed pre-treatment baseline, revealing specific binge-related risk when discontinuing GLP-1RAs.",
  "abstract_shown": true,
  "affiliations": [
    "University of Pittsburgh School of Medicine"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "B. A. Hildebrandt"
    },
    {
      "name": "S. E. Ahmari"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6azjg452sfaer.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.11.02.763781",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.11.02.763781v1.full",
  "id": "6azjg452sfaer",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.11.02.763781v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "animal behavior and cognition"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.11.02.763781v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-02",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/6azjg452sfaer.ris",
  "sources": [
    {
      "first_seen": "2026-11-05T00:21:36Z",
      "native_id": "10.64898/2026.11.02.763781",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.11.02.763781v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "biorxiv:animal behavior and cognition",
      "subfield": "zoology-behaviour"
    }
  ],
  "title": "Discontinuation of GLP-1RA Treatment Reinstates Binge-Like Eating and Drives Body Weight Past Pre-Treatment Levels in Mice",
  "title_text": "Discontinuation of GLP-1RA Treatment Reinstates Binge-Like Eating and Drives Body Weight Past Pre-Treatment Levels in Mice",
  "type": "preprint",
  "updated_at": "2026-11-06T00:21:25Z",
  "url": "https://research.draconitic.com/paper/6azjg452sfaer",
  "venue": "bioRxiv",
  "versions": []
}