{
  "abstract": "The brain processes information across distributed circuits, yet a typical experiment records only a few regions, leaving the rest unobserved. Connectivity and latent-embedding methods relate brain regions but do not return the waveform of an unrecorded one. Here we introduce NeuroGate, a framework for cross-regional neural signal translation that recovers an unrecorded region's waveform from a recorded one. Across 56 pathways spanning rodent LFP, human sEEG and ECoG, and scalp EEG, NeuroGate predicts waveforms more accurately than 13 deep-learning and linear baselines, with low across-session variance and high median accuracy. We tested the predictions against a circuit perturbation: silencing piriform-cortex output with tetanus toxin light chain collapsed piriform-to-bulb predictions in 8 of 8 folds while the reverse was preserved, matching the monosynaptic anatomy. We demonstrate two applications: quantifying how recording redundancy bounds the information from each added source, and a reusable perturbation protocol for verifying directional translation in any circuit.",
  "abstract_shown": true,
  "affiliations": [
    "Istanbul Medipol University"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "A. Zareh"
    },
    {
      "name": "M. K. Ozdemir"
    },
    {
      "name": "R. Yagci"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6cffx2wjdwt9q.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.09.09.750499",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.09.09.750499v1.full",
  "id": "6cffx2wjdwt9q",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.09.09.750499v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "neuroscience"
    ],
    [
      "openalex",
      "2805|Neural dynamics and brain function"
    ]
  ],
  "openalex": "W7213332938",
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.09.09.750499v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-09",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/6cffx2wjdwt9q.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:22:34Z",
      "native_id": "10.64898/2026.09.09.750499",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.09.09.750499v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "biorxiv:neuroscience",
      "subfield": "neuroscience"
    }
  ],
  "title": "NeuroGate: waveform translation between brain",
  "title_text": "NeuroGate: waveform translation between brain",
  "type": "preprint",
  "updated_at": "2026-10-30T12:22:34Z",
  "url": "https://research.draconitic.com/paper/6cffx2wjdwt9q",
  "venue": "bioRxiv",
  "versions": []
}