{
  "abstract": "Intermolecular aza Paternò–Büchi (aPB) reactions provide a direct and convergent approach to azetidines through the photocycloaddition of imines and alkenes. However, reactions involving unactivated alkenes remain challenging, particularly with acyclic imines, whose excited states are susceptible to rapid nonradiative relaxation and competing photochemical pathways. Here, we report N-phosphinyl imines as readily accessible and stable photoreactive partners for visiblelight-mediated intermolecular aPB reactions with unactivated alkenes. Triplet sensitization using thioxanthone as an inexpensive organic photocatalyst enables productive [2+2]-cycloaddition across a range of alkenes, establishing a new reagent platform for intermolecular aPB chemistry to expand the accessible reactivity of acyclic imines with unactivated alkenes.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Chemistry, University of British Columbia, 203 Main Mall, Vancouver, BC, Canada, V6T 1Z1",
    "Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC, Canada, V6T 1Z3",
    "BC Cancer Research Institute, 675 West 10th Ave, Vancouver, BC, Canada, V5Z 1L3"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Scott L. Kim"
    },
    {
      "affs": [
        1
      ],
      "name": "Lillian J. Carleu"
    },
    {
      "affs": [
        2
      ],
      "name": "Corinna S. Schindler",
      "orcid": "0000-0003-4968-8013"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6d0eexernm277.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15007906/v2",
  "fulltext_url": null,
  "id": "6d0eexernm277",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15007906/v2",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1605|Radical Photochemical Reactions"
    ]
  ],
  "openalex": "W7213920506",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15007906/v2",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-20",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/6d0eexernm277.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:19Z",
      "native_id": "10.26434/chemrxiv.15007906",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15007906/v2"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Radical Photochemical Reactions",
      "subfield": "organic"
    }
  ],
  "title": "N-Phosphoryl Imines Enable Intermolecular Aza Paternò–Büchi Reactions with Unactivated and Activated Alkenes",
  "title_text": "N-Phosphoryl Imines Enable Intermolecular Aza Paternò–Büchi Reactions with Unactivated and Activated Alkenes",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:19Z",
  "url": "https://research.draconitic.com/paper/6d0eexernm277",
  "venue": "ChemRxiv",
  "versions": []
}