{
  "abstract": "Management of treatment-resistant psychosis is inherently complex, presenting unique clinical challenges in pediatric populations when metabolic syndrome risk limits pharmacologic options. We report a case of an adolescent with rapid decline and persistent psychotic symptoms despite trials of first-line antipsychotic agents. His refractory clinical course required careful consideration of the relative benefits of other antipsychotic therapies against their potential for significant metabolic adverse effects. Clinical decision-making was further complicated by the need to engage the patient's mother in consent discussions and shared treatment decisions. This case highlights the clinical challenges of treating pediatric treatment-resistant psychosis while balancing psychiatric stabilization, cardiometabolic risks, and family-centered consent.",
  "abstract_shown": true,
  "affiliations": [
    "Psychiatry and Behavioral Sciences, New York Institute of Technology (NYIT) College of Osteopathic Medicine, Old Westbury, USA.",
    "Psychiatry and Behavioral Sciences, Nassau University Medical Center, East Meadow, USA."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Michael Belkin"
    },
    {
      "affs": [
        1
      ],
      "name": "Jasmin Grewal"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6d69629bm5c6v.bib",
  "cited_by": 0,
  "doi": "10.7759/cureus.116658",
  "fulltext_url": "https://europepmc.org/articles/PMC13686321",
  "id": "6d69629bm5c6v",
  "issns": [
    "2168-8184"
  ],
  "landing_url": "https://europepmc.org/article/MED/42910034",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2738|Schizophrenia research and treatment"
    ]
  ],
  "openalex": "W7213910487",
  "pdf_url": "https://europepmc.org/articles/PMC13686321?pdf=render",
  "pmcid": "PMC13686321",
  "pmid": "42910034",
  "published": "2026-09-21",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/6d69629bm5c6v.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:14Z",
      "native_id": "MED:42910034",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42910034"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2738|Schizophrenia research and treatment",
      "subfield": "psychiatry"
    }
  ],
  "title": "Treatment-Resistant Psychosis in an Adolescent at Risk of Metabolic Syndrome: A Case Report.",
  "title_text": "Treatment-Resistant Psychosis in an Adolescent at Risk of Metabolic Syndrome: A Case Report.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:14Z",
  "url": "https://research.draconitic.com/paper/6d69629bm5c6v",
  "venue": "Cureus",
  "versions": []
}