{
  "abstract": "Surface wrinkle instabilities in bilayer soft materials underpin a wide range of applications, from tunable optics to metrology and mechanobiology. We present a novel technique for dynamic, reconfigurable wrinkle patterns: exposing a polydimethylsiloxane (PDMS) cylindrical block to infrared laser creates a micrometer thick, highly cross-linked rigid layer. Subsequent uniaxial compression generates sinusoidal wrinkles oriented perpendicular to the compression direction. Dynamic reconfiguration via a custom rotation device involves wrinkle rotation, fragmentation, and reassociation, exhibiting S-like bending, defect nucleation, propagation, and annihilation. These dynamics are qualitatively captured by the anisotropic Swift-Hohenberg equation. The experimental setup is compatible with upright confocal microscopy, enabling real-time visualization of cellular interactions with evolving wrinkle topography. Living cells attach, migrate, and align/coordinate with traveling waves. This work opens new avenues for investigating cell migration guided by dynamic substrate curvature and introduces a versatile platform for dynamic surface control and studying topological defect physics.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 16,
  "authors": [
    {
      "name": "Khoa Dang Cao"
    },
    {
      "name": "Ismail Tahmaz"
    },
    {
      "name": "Hung Quoc Tran"
    },
    {
      "name": "Marie-Ly Chapon"
    },
    {
      "name": "Tatiana Petithory"
    },
    {
      "name": "Aissam Airoudj"
    },
    {
      "name": "Patrick Lamielle"
    },
    {
      "name": "Luc Delmotte"
    },
    {
      "name": "Carole Arnold"
    },
    {
      "name": "Karine Anselme"
    },
    {
      "name": "Ian Manifacier"
    },
    {
      "name": "Gildas Carlin"
    },
    {
      "name": "Maxime Vassaux"
    },
    {
      "name": "Laurent Pieuchot"
    },
    {
      "name": "Jean-Louis Milan"
    },
    {
      "name": "Valeriy Luchnikov"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6ebfm4v4w7n4d.bib",
  "cited_by": 0,
  "doi": "10.1016/j.xcrp.2026.103520",
  "fulltext_url": null,
  "id": "6ebfm4v4w7n4d",
  "issns": [
    "2666-3864"
  ],
  "landing_url": "https://hal.science/hal-05738189v2",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.phys"
    ],
    [
      "hal",
      "0.sdv"
    ],
    [
      "openalex",
      "2210|Advanced Materials and Mechanics"
    ]
  ],
  "openalex": "W7204854357",
  "pdf_url": "https://hal.science/hal-05738189/document",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-30",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/6ebfm4v4w7n4d.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:33Z",
      "native_id": "hal-05738189",
      "source": "hal",
      "url": "https://hal.science/hal-05738189v2"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:0.sdv",
      "subfield": "general"
    },
    {
      "field": "physics",
      "origin": "hal:0.phys",
      "subfield": "general"
    }
  ],
  "title": "A programmable platform for the study of active wrinkle patterns and cell migration directed by dynamic curvotaxis",
  "title_text": "A programmable platform for the study of active wrinkle patterns and cell migration directed by dynamic curvotaxis",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:33Z",
  "url": "https://research.draconitic.com/paper/6ebfm4v4w7n4d",
  "venue": "Cell Reports Physical Science",
  "versions": []
}