{
  "abstract": "Adolescent cannabis use produces lasting and sex-specific effects into adulthood, although poorly explained mechanistically. This study links these cannabis-induced effects to sex-dependent changes in phosphorylation of mitochondrial Complex I subunit NDUFS4 during adolescence, identifying mitochondrial pathways as causal mechanisms and potential therapeutic targets to reduce their long-term consequences.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 12,
  "authors": [
    {
      "name": "Christina Ioannidou"
    },
    {
      "name": "Irene Manzanares-Sierra"
    },
    {
      "name": "Daniel Jimenez-Blasco"
    },
    {
      "name": "Darío García-Rodriguez"
    },
    {
      "name": "Israel Manjarrés-Raza"
    },
    {
      "name": "Francisca Julio-Kalajzić"
    },
    {
      "name": "Antonio C Pagano Zottola"
    },
    {
      "name": "Martina Di Bartolomeo"
    },
    {
      "name": "Guillaume Ferreira"
    },
    {
      "name": "Juan P Bolaños"
    },
    {
      "name": "Giovanni Marsicano"
    },
    {
      "name": "Arnau Busquets-Garcia"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6egyg284p6wqg.bib",
  "cited_by": 0,
  "doi": "10.1038/s41386-026-02539-3",
  "fulltext_url": null,
  "id": "6egyg284p6wqg",
  "issns": [
    "0893-133X",
    "0007-0920"
  ],
  "landing_url": "https://u-bordeaux.hal.science/hal-05745987v1",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "hal",
      "1.sdv.neu"
    ],
    [
      "openalex",
      "2736|Cannabis and Cannabinoid Research"
    ]
  ],
  "openalex": "W7204473123",
  "pdf_url": "https://u-bordeaux.hal.science/hal-05745987/document",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-27",
  "publisher": "Nature Publishing Group",
  "ris": "https://research.draconitic.com/paper/6egyg284p6wqg.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:33Z",
      "native_id": "hal-05745987",
      "source": "hal",
      "url": "https://u-bordeaux.hal.science/hal-05745987v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:1.sdv.neu",
      "subfield": "neuroscience"
    }
  ],
  "title": "A transient mitochondrial switch underlies long lasting effects of adolescent cannabis",
  "title_text": "A transient mitochondrial switch underlies long lasting effects of adolescent cannabis",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:33Z",
  "url": "https://research.draconitic.com/paper/6egyg284p6wqg",
  "venue": "Neuropsychopharmacology",
  "versions": []
}