{
  "abstract": "Background: Vibrio vulnificus (V. vulnificus) is a highly aggressive pathogen that causes rapidly progressing necrotizing fasciitis and septic shock, frequently leading to limb amputation or death. Limb salvage in this setting remains challenging, particularly in diabetic patients.\n\nCase presentation: A 72-year-old diabetic male developed V. vulnificus necrotizing fasciitis of the left upper limb after handling marine fish, presenting with local erythema, swelling, warmth, pain, and septic shock. He underwent five sequential debridement procedures combined with vacuum sealing drainage (VSD), followed by artificial dermis application and split-thickness skin grafting, ultimately achieving successful limb salvage.\n\nConclusion: In this patient, serial reassessment, staged debridement with VSD, and delayed wound reconstruction were associated with infection control and limb preservation. This case may inform the multidisciplinary management of severe V. vulnificus necrotizing fasciitis.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Plastic Surgery and Burns Center, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, China",
    "Plastic Surgery Institute, Shantou University Medical College, Shantou, Guangdong, China",
    "Shantou Plastic Surgery Clinical Research Center, Shantou, Guangdong, China",
    "Research Center of Translational Medicine, Second Affiliated Hospital, Shantou University Medical College, Shantou, Guangdong, China"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Yang Chen"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Mengjing Xu"
    },
    {
      "affs": [
        1,
        2,
        3
      ],
      "name": "Shukai Zheng"
    },
    {
      "affs": [
        1,
        2,
        3
      ],
      "name": "Liyun Chen"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Zijian Huang"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Weiping Zeng"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Yang Hao"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Shijie Tang"
    },
    {
      "affs": [
        0,
        1,
        2,
        3
      ],
      "name": "Wancong Zhang"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6njw03w1jy21j.bib",
  "cited_by": 0,
  "doi": "10.3389/fsurg.2026.1944678",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13731324/",
  "id": "6njw03w1jy21j",
  "issns": [
    "2296-875X"
  ],
  "landing_url": "https://doi.org/10.3389/fsurg.2026.1944678",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "openalex",
      "2404|Vibrio bacteria research studies"
    ]
  ],
  "openalex": "W7223091499",
  "pdf_url": "https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2026.1944678/pdf",
  "pmcid": "PMC13731324",
  "pmid": "42984619",
  "published": "2026-10-21",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/6njw03w1jy21j.ris",
  "sources": [
    {
      "first_seen": "2026-11-08T12:21:33Z",
      "native_id": "PMC13731324",
      "source": "pmc",
      "url": "https://doi.org/10.3389/fsurg.2026.1944678"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2404|Vibrio bacteria research studies",
      "subfield": "microbiology"
    }
  ],
  "title": "Case Report: Limb salvage in Vibrio vulnificus necrotizing fasciitis through sequential debridement and skin grafting",
  "title_text": "Case Report: Limb salvage in Vibrio vulnificus necrotizing fasciitis through sequential debridement and skin grafting",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T12:21:33Z",
  "url": "https://research.draconitic.com/paper/6njw03w1jy21j",
  "venue": "Frontiers in Surgery",
  "versions": []
}