{
  "abstract": "Breast hamartomas are rare, benign lesions composed of adipose, fibrous and glandular tissue. While typically non-malignant and not linked to increased breast cancer risk, they are often underdiagnosed due to variable imaging and histological features. We report a rare case of ductal carcinoma in situ (DCIS) with microinvasion arising within a mammary hamartoma. Unexpectedly the patient went on to develop a triple-negative invasive breast cancer 6 months following nipple-sparing mastectomy and implant reconstruction. To date, only 16 cases of breast carcinoma within hamartomas have been reported, making this case an important addition to the limited literature. It highlights the need for careful imaging interpretation, pathological review and multidisciplinary management, particularly in lesions with glandular components or atypical features. With increasing use of breast imaging, identification of hamartomas is expected to rise, making awareness of their rare malignant potential essential. In the absence of prevalence data or management guidelines, this case underscores the value of centralised reporting and collaborative clinical decision-making.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Breast Surgery St. George's Hospital NHS Foundation Trust Blackshaw Road SW17 0QT London UK nhs.uk.",
    "Department of Histopathology Kingston Hospital Kingston and Richmond NHS Foundation Trust Kingston Upon Thames KT2 7QB, Galsworthy Rd London UK kingstonhospital.nhs.uk.",
    "Department of Clinical Radiology Kingston Hospital Kingston and Richmond NHS Foundation Trust Galsworthy Rd, Kingston Upon Thames KT2 7QB London UK kingstonhospital.nhs.uk.",
    "Royal Marsden Institute of Cancer Research London UK icr.ac.uk.",
    "Kingston Hospital Kingston and Richmond NHS Foundation Trust Galsworthy Rd, Kingston Upon Thames KT2 7QB London UK kingstonhospital.nhs.uk."
  ],
  "article_type": "case study",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Buket Ertansel",
      "orcid": "0000-0001-8388-569X"
    },
    {
      "affs": [
        1
      ],
      "name": "Geetha Joseph",
      "orcid": "0009-0002-5886-172X"
    },
    {
      "affs": [
        2
      ],
      "name": "Oniaza Syed",
      "orcid": "0009-0002-8610-3555"
    },
    {
      "affs": [
        3
      ],
      "name": "Anna Kirby",
      "orcid": "0009-0008-5673-0199"
    },
    {
      "affs": [
        4
      ],
      "name": "Marina Parton",
      "orcid": "0000-0002-1407-4460"
    },
    {
      "affs": [
        0
      ],
      "name": "Sarah Shuk-Kay Tang",
      "orcid": "0000-0002-9148-7525"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6p0390d0vg8t7.bib",
  "cited_by": 0,
  "doi": "10.1155/cris/1681410",
  "fulltext_url": "https://europepmc.org/articles/PMC13711491",
  "id": "6p0390d0vg8t7",
  "issns": [
    "2090-6900",
    "2090-6919"
  ],
  "landing_url": "https://europepmc.org/article/MED/42948616",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Article"
    ],
    [
      "heading",
      "Case Report"
    ],
    [
      "openalex",
      "2734|Breast Lesions and Carcinomas"
    ]
  ],
  "openalex": "W7224011320",
  "pdf_url": "https://europepmc.org/articles/PMC13711491?pdf=render",
  "pmcid": "PMC13711491",
  "pmid": "42948616",
  "published": "2026-10-27",
  "publisher": "Wiley",
  "ris": "https://research.draconitic.com/paper/6p0390d0vg8t7.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:33Z",
      "native_id": "MED:42948616",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42948616"
    },
    {
      "first_seen": "2026-10-31T12:22:15Z",
      "native_id": "PMC13711491",
      "source": "pmc",
      "url": "https://doi.org/10.1155/cris/1681410"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "journal-openalex:2746|Gastrointestinal disorders and treatments",
      "subfield": "surgery"
    }
  ],
  "title": "Ductal Carcinoma In Situ With Microinvasion Arising in a Breast Hamartoma: A Case Report and Review of Guidelines of Hamartoma Management.",
  "title_text": "Ductal Carcinoma In Situ With Microinvasion Arising in a Breast Hamartoma: A Case Report and Review of Guidelines of Hamartoma Management.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T12:22:15Z",
  "url": "https://research.draconitic.com/paper/6p0390d0vg8t7",
  "venue": "Case reports in surgery",
  "versions": []
}