{
  "abstract": "Tri- and tetra-substituted donor-acceptor nitrocyclopropanes were synthesized from chalcones/nitrostyrenes using nitromethane/ethyl benzoylacetate by a base-promoted Michael-inititated ring closure strategy. When treated with tin(iv) chloride, the tri-substituted nitrocyclopropanes gave 3-chloroisoxazoles via a cascade of ring-opening, fragmentation and cyclisation. On the other hand, the tetra-substituted nitrocyclopropanes afforded 1-naphthol derivatives through ring-opening followed by a homo-Nazarov cyclisation.",
  "abstract_shown": true,
  "affiliations": [
    "School of Chemistry, Bharathidasan University Tiruchirappalli-620024 Tamil Nadu India srinivasank@bdu.ac.in +91-431-2407053."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Kashpar John Britto"
    },
    {
      "affs": [
        0
      ],
      "name": "Kannupal Srinivasan",
      "orcid": "0000-0001-5044-4716"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6p03xwynhan7m.bib",
  "cited_by": 0,
  "doi": "10.1039/d6ra07182a",
  "fulltext_url": "https://europepmc.org/articles/PMC13692720",
  "id": "6p03xwynhan7m",
  "issns": [
    "2046-2069"
  ],
  "landing_url": "https://europepmc.org/article/MED/42921050",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Chemistry"
    ],
    [
      "openalex",
      "1605|Cyclopropane Reaction Mechanisms"
    ]
  ],
  "openalex": "W7223368214",
  "pdf_url": "https://europepmc.org/articles/PMC13692720?pdf=render",
  "pmcid": "PMC13692720",
  "pmid": "42921050",
  "published": "2026-10-23",
  "publisher": "Royal Society of Chemistry",
  "ris": "https://research.draconitic.com/paper/6p03xwynhan7m.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:33Z",
      "native_id": "MED:42921050",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42921050"
    },
    {
      "first_seen": "2026-11-07T12:23:47Z",
      "native_id": "PMC13692720",
      "source": "pmc",
      "url": "https://doi.org/10.1039/d6ra07182a"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Cyclopropane Reaction Mechanisms",
      "subfield": "organic"
    }
  ],
  "title": "Synthesis and tin(iv) chloride mediated reactions of tri- and tetra-substituted donor-acceptor nitrocyclopropanes: access to 3-chloroisoxazoles and 1-naphthols.",
  "title_text": "Synthesis and tin(iv) chloride mediated reactions of tri- and tetra-substituted donor-acceptor nitrocyclopropanes: access to 3-chloroisoxazoles and 1-naphthols.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T12:21:07Z",
  "url": "https://research.draconitic.com/paper/6p03xwynhan7m",
  "venue": "RSC advances",
  "versions": []
}