{
  "abstract": "Guava (Psidium guajava L.) leaves are increasingly processed into caffeine-free herbal teas, valued for their rich phenolic composition and cultivar-dependent sensory profile. However, no systematic study has yet resolved how cultivar identity shapes the volatile, non-volatile, and functional dimensions of the finished tea. Here, eight guava tea cultivars were profiled using a multi-platform approach combining electronic nose sensing, headspace GC-MS, electronic-tongue analysis, non-targeted and targeted LC-MS metabolomics, and physicochemical indices. The eight cultivars were described by three volatile composition patterns: (i) a monoterpene-rich group, most pronounced in 'Yanzhi Hong', (ii) a compositionally diverse non-monoterpene group dominated by sesquiterpene esters and alkanes, and (iii) a group with a lower abundance of most discriminant volatiles-a pattern consistent across electronic nose sensor responses and GC-MS compound-level data. Electronic-tongue profiling identified largely independent instrumental taste-response modules. Instrumental astringency showed a robust, cross-platform-supported association with cultivars enriched in flavonoid glycosides (sparse partial least squares [sPLS] Q² = 0.733-0.900), whereas bitterness was statistically detectable but compositionally unresolved. Antioxidant (DPPH) capacity was only weakly associated with total phenolic and flavonoid contents (r = 0.188 for each), indicating that bulk phenolic indices alone did not adequately explain cultivar-level DPPH variation. Integrating these results into a candidate pathway-output framework indicated that aroma, taste, and antioxidant-related quality are shaped by partially independent metabolic axes rather than a single quality gradient. These findings provide a candidate-based, cultivar-resolved framework for guava leaf tea quality and identify candidate cultivars suited to terpene-rich, non-monoterpene, or phenolic-retention-oriented product development.",
  "abstract_shown": true,
  "affiliations": [
    "Guangxi Subtropical Crops Research Institute, Guangxi Academy of Agricultural Sciences, Nanning 530001, China.",
    "Key Laboratory of Quality and Safety Control for Subtropical Fruit and Vegetable, Ministry of Agriculture and Rural Affairs, Nanning 530001, China.",
    "Guangxi Key Laboratory of Quality and Safety Control for Subtropical Fruits, Guangxi Subtropical Crops Research Institute, Nanning 530001, China."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Songqiong Ma"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Shimiao Chen",
      "orcid": "0000-0002-5904-4695"
    },
    {
      "affs": [
        0
      ],
      "name": "Lin Ning"
    },
    {
      "affs": [
        0
      ],
      "name": "Jingsheng Fan"
    },
    {
      "affs": [
        0
      ],
      "name": "Jingwen Ai"
    },
    {
      "affs": [
        0
      ],
      "name": "Haojun Chen"
    },
    {
      "affs": [
        0
      ],
      "name": "Jiang He"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Qinyu Lu",
      "orcid": "0000-0001-6075-9471"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Gan-Lin Chen",
      "orcid": "0000-0003-0076-5268"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6pqs8gm9xr74q.bib",
  "cited_by": 0,
  "doi": "10.3390/foods15203616",
  "fulltext_url": "https://europepmc.org/articles/PMC13704376",
  "id": "6pqs8gm9xr74q",
  "issns": [
    "2304-8158"
  ],
  "landing_url": "https://europepmc.org/article/MED/42940252",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "3004|Psidium guajava Extracts and Applications"
    ]
  ],
  "openalex": "W7221519555",
  "pdf_url": "https://europepmc.org/articles/PMC13704376?pdf=render",
  "pmcid": "PMC13704376",
  "pmid": "42940252",
  "published": "2026-10-11",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/6pqs8gm9xr74q.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:22:24Z",
      "native_id": "MED:42940252",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42940252"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:3004|Psidium guajava Extracts and Applications",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "Multi-Platform Metabolomic and Sensory Profiling Reveals Cultivar-Dependent Volatile, Taste, and Antioxidant Chemotypes in Guava Leaf Tea.",
  "title_text": "Multi-Platform Metabolomic and Sensory Profiling Reveals Cultivar-Dependent Volatile, Taste, and Antioxidant Chemotypes in Guava Leaf Tea.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:22:24Z",
  "url": "https://research.draconitic.com/paper/6pqs8gm9xr74q",
  "venue": "Foods (Basel, Switzerland)",
  "versions": []
}