{
  "abstract": "Key Findings WHAT WAS KNOWN? Underreporting of neonatal admissions and mortality is common in many countries, particularly for neonates <1000g, leading to underestimation of in-patient neonatal mortality rates (iNMRs). This has important implications for comparing between hospitals or over time, evaluation of interventions, as well as planning resource allocation and tracking progress towards SDG 3.2 for newborn survival. WHAT WAS DONE THAT IS NEW? Based on context-specific data, a simulation-based approach was used to develop birthweight-specific adjustment functions to account for underreporting of admissions and in-patient neonatal deaths. Various levels of underreporting were then introduced, and adjustment models were re-fitted to estimate the original simulated values. The approach was extended to adjust for underreporting of admissions and deaths in 65 hospitals partnering with NEST360 in four countries (Kenya, Malawi, Nigeria, and Tanzania). Adjustment curves were developed using data from 26 hospitals with plausible mortality rates (≥700 deaths per 1000 live births for neonates <1000g) to create robust birthweight-specific adjustment functions. These functions were then applied across data from all 65 hospitals to adjust for underreporting in a dataset of 172,809 baseline in-patient neonatal mortality admissions. WHAT WAS FOUND? Applying birthweight-specific adjustment functions to simulated data demonstrated the statistical approach to be robust in adjusting for underreporting, since adjusted neonatal iNMRs closely matched the original simulated values (\"truth\") even at varying levels of underreporting. Using a dataset of 172,809 admissions from 65 hospitals partnering with NEST360, unadjusted iNMRs were 121 deaths per 1000 admissions in Nigeria, 128 per 1000 in Tanzania, 132 per 1000 in Malawi, and 135 per 1000 in Kenya. Birthweight-specific adjustment functions were developed based on 26 hospitals with plausible mortality rates (≥700 deaths per 1000 live births for neonates <1000g). After applying adjustment curves, the iNMRs increased to 162 deaths per 1000 admissions in Nigeria, 183 per 1000 in Tanzania, 174 per 1000 in Malawi, and 172 per 1000 in Kenya. As expected, adjusted iNMRs were higher and reduced inter-hospital variability. WHAT NEXT? This adjustment method may be useful more widely, including in LMIC national routine health data, which is now the main source of neonatal data, given recent defunding of Demographic Health Surveys. Share learning to improve capture of all admissions and deaths in routine data systems, such as increased communication that all live-born babies are to be registered, irrespective of gestational age or weight, regular data audits, and educating/mentoring to promote accurate and complete reporting.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Infectious Disease Epidemiology and International Health, London School of Hygiene & Tropical Medicine",
    "The University of Hong Kong",
    "Research Support Center, School of Public Health and Family Medicine, Kamuzu University of Health Sciences",
    "Health Systems Impact Evaluation and Policy Department, Ifakara Health Institute",
    "Rice360 Institute for Global Health Technologies, Rice University",
    "Kenya Medical Research Institute-Wellcome Trust",
    "Aga Khan University",
    "APIN Public Health Initiatives"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 30,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Lucas Malla"
    },
    {
      "affs": [
        1
      ],
      "name": "Siu Nam Wong"
    },
    {
      "affs": [
        2
      ],
      "name": "Samuel Ngwala"
    },
    {
      "affs": [
        2
      ],
      "name": "Evelyn Zimba"
    },
    {
      "affs": [
        2
      ],
      "name": "Msandeni Chiume"
    },
    {
      "affs": [
        2
      ],
      "name": "Norman Lufesi"
    },
    {
      "affs": [
        2
      ],
      "name": "Kondwani Kawaza"
    },
    {
      "affs": [
        3
      ],
      "name": "Honorati Masanja"
    },
    {
      "affs": [
        0
      ],
      "name": "Josephine Shabani"
    },
    {
      "affs": [
        3
      ],
      "name": "Prosper Mshana"
    },
    {
      "affs": [
        3
      ],
      "name": "Robert Tillya"
    },
    {
      "affs": [
        3
      ],
      "name": "Nahya Salim"
    },
    {
      "affs": [
        4
      ],
      "name": "John Wainaina"
    },
    {
      "affs": [
        4
      ],
      "name": "Julius Thomas"
    },
    {
      "affs": [
        4
      ],
      "name": "Junwei Chen"
    },
    {
      "affs": [
        5
      ],
      "name": "Franklin Okech"
    },
    {
      "affs": [
        4
      ],
      "name": "George Okello"
    },
    {
      "affs": [
        6
      ],
      "name": "William Macharia"
    },
    {
      "affs": [
        7
      ],
      "name": "Olabisi Dosunmu"
    },
    {
      "affs": [
        4
      ],
      "name": "Chinyere Ezeaka"
    },
    {
      "affs": [
        4
      ],
      "name": "Opeyemi Odedere"
    },
    {
      "affs": [
        0
      ],
      "name": "Morris Ogero"
    },
    {
      "affs": [
        0
      ],
      "name": "James H. Cross"
    },
    {
      "affs": [
        0
      ],
      "name": "Rebecca E. Penzias"
    },
    {
      "affs": [
        4
      ],
      "name": "Christine Bohne"
    },
    {
      "affs": [
        4
      ],
      "name": "Rebecca Richards-Kortum"
    },
    {
      "affs": [
        4
      ],
      "name": "Maria Oden"
    },
    {
      "affs": [
        0
      ],
      "name": "Eric O. Ohuma"
    },
    {
      "affs": [
        0
      ],
      "name": "Joy E. Lawn"
    },
    {
      "name": "with NEST360 Collaborative authorship group"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6q1mdvf4bn348.bib",
  "cited_by": 0,
  "doi": "10.1186/s12963-026-00496-z",
  "fulltext_url": "https://doi.org/10.1186/s12963-026-00496-z",
  "id": "6q1mdvf4bn348",
  "issns": [
    "1478-7954"
  ],
  "landing_url": "https://doi.org/10.1186/s12963-026-00496-z",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "R858-859.7"
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    [
      "lcc",
      "RA1-1270"
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    [
      "openalex",
      "3600|Maternal and Neonatal Healthcare"
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  "openalex": "W7171553805",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-01",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/6q1mdvf4bn348.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:46:18Z",
      "native_id": "0dc5b996e7654d31a2104b2ede0f4ffd",
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  "subjects": [
    {
      "field": "medicine",
      "origin": "lcc:RA1-1270",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Neonatal admissions and mortality: a statistical adjustment approach using birthweight-specific curves to address bias due to underreporting in 65 hospitals in four African countries",
  "title_text": "Neonatal admissions and mortality: a statistical adjustment approach using birthweight-specific curves to address bias due to underreporting in 65 hospitals in four African countries",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:46:18Z",
  "url": "https://research.draconitic.com/paper/6q1mdvf4bn348",
  "venue": "Population Health Metrics",
  "versions": []
}