{
  "abstract": "Background: Although therapeutic advances have prolonged survival in hematologic malignancies, these conditions may still significantly impair patients’ functioning and health-related quality of life (HRQoL). Objective: To assess HRQoL and selected socioeconomic, psychological, and physical factors in patients with hematologic malignancies receiving outpatient care. Materials and Methods: This study included 94 patients: 33 with chronic lymphocytic leukemia, 30 with plasma cell myeloma, and 31 with follicular lymphoma. The mean age of participants was 61.5 ± 13.2 years. HRQoL was measured using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-C30 version 3.0 (EORTC QLQ-C30); anxiety was evaluated using the State-Trait Anxiety Inventory (STAI); psychological adjustment to cancer was assessed using the Mini-Mental Adjustment to Cancer (Mini-MAC) scale; and dominant-hand grip strength was recorded. Differences between groups and factors associated with global health status/quality of life were analyzed. Results: The median global health status/quality-of-life score (QL2) was 66.66 (IQR: 25.00) in patients with chronic lymphocytic leukemia, 58.33 (IQR: 16.67) in patients with multiple myeloma, and 58.33 (IQR: 16.67) in patients with follicular lymphoma, on a 0–100 scale. Differences among diagnostic groups did not reach the predefined threshold for statistical significance (H(2, N = 94) = 5.7; p = 0.057). The median state anxiety score was 35.50 points (IQR:12), and the median trait anxiety score was 44.50 points (IQR:14). Significant differences between diagnoses were identified for trait anxiety (H(2, N = 94) = 16.76; p = 0.0002), whereas no statistically significant differences were observed for state anxiety (H(2, N = 94) = 5.19; p = 0.070). Moderate levels of constructive coping (median 44.00 points, IQR:5) and low levels of destructive coping (median 24.50 points, IQR:11) were observed, indicating a predominance of adaptive coping strategies; no significant between-group differences were detected. The median dominant-hand grip strength was 28 kg (IQR:18 kg), with no significant differences between diagnoses. Regression analysis showed that financial difficulties, trait anxiety, and dominant-hand grip strength were independently associated with the QL2 score (R2 = 0.431; p < 0.001). Conclusions: Financial difficulties, trait anxiety, and dominant-hand grip strength were independently associated with global health status/quality of life in patients with hematologic malignancies receiving outpatient care, although the cross-sectional design precludes causal conclusions.",
  "abstract_shown": true,
  "affiliations": [
    "Lower Silesian Oncology, Pulmonology and Hematology Center, 53-439 Wrocław, Poland",
    "Department of Psychology, Pomeranian University in Słupsk, 76-200 Słupsk, Poland",
    "Department of Hematology and Bone Marrow Transplantation, Janusz Korczak Regional Specialist Hospital in Słupsk Ltd., 76-200 Słupsk, Poland",
    "Faculty of Physiotherapy, Wrocław University of Health and Sport Sciences, 51-612 Wrocław, Poland"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Małgorzata Pudełek"
    },
    {
      "affs": [
        0
      ],
      "name": "Jarosław Dybko",
      "orcid": "0000-0003-3555-2887"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Sebastian Zdończyk"
    },
    {
      "affs": [
        3
      ],
      "name": "Iwona Malicka",
      "orcid": "0000-0002-7668-001X"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6qym1enmrdtrc.bib",
  "cited_by": 0,
  "doi": "10.3390/jcm15218545",
  "fulltext_url": null,
  "id": "6qym1enmrdtrc",
  "issns": [
    "2077-0383"
  ],
  "landing_url": "https://www.mdpi.com/2077-0383/15/21/8545",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-03",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/6qym1enmrdtrc.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T12:21:42Z",
      "native_id": "10.3390/jcm15218545",
      "source": "crossref",
      "url": "https://www.mdpi.com/2077-0383/15/21/8545"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "journal-openalex:F27",
      "subfield": "general"
    }
  ],
  "title": "Quality of Life Among Patients with Hematologic Malignancies Receiving Outpatient Care: Associations with Socioeconomic, Clinical, Psychological, and Physical Factors",
  "title_text": "Quality of Life Among Patients with Hematologic Malignancies Receiving Outpatient Care: Associations with Socioeconomic, Clinical, Psychological, and Physical Factors",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T00:21:25Z",
  "url": "https://research.draconitic.com/paper/6qym1enmrdtrc",
  "venue": "Journal of Clinical Medicine",
  "versions": []
}