{
  "abstract": "Upper gastrointestinal bleed (UGIB) is a significant and potentially life-threatening complication in renal transplant recipients, frequently associated with immunosuppressive therapy. We present a case of a 38-year-old male renal transplant recipient who experienced recurrent UGIB due to duodenal and gastric ulcers during the early postoperative period. His immunosuppressive regimen, initially consisting of antithymocyte globulin, steroids, tacrolimus, and mycophenolate mofetil (MMF), was adjusted multiple times in response to persistent bleeding episodes. Despite numerous endoscopic, radiological, and surgical interventions, his condition necessitated further immunosuppressive modulation, including cessation of MMF and introduction of belatacept, which ultimately stabilized his gastrointestinal condition. This case underscores the complexities of managing UGIB in renal transplant recipients under immunosuppressive therapy and highlights the need for a tailored multidisciplinary approach to optimize outcomes while preserving graft function.",
  "abstract_shown": true,
  "affiliations": [
    "Internal Medicine Residency Program (IMRP), Division of Internal Medicine, Hamad Medical Corporation, Doha, Qatar",
    "Department of Gastroenterology, Hamad Medical Corporation, Doha, Qatar"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Elhassan Mahmoud",
      "orcid": "0000-0001-8528-0272"
    },
    {
      "affs": [
        1
      ],
      "name": "Yousra Ali"
    },
    {
      "affs": [
        1
      ],
      "name": "Ibrahim M. Obeidat"
    },
    {
      "affs": [
        1
      ],
      "name": "Souraia Mezhoud"
    },
    {
      "affs": [
        1
      ],
      "name": "Rafie A. Yakoob"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6r8qs0rqyb62k.bib",
  "cited_by": 0,
  "doi": "10.1177/2050313x261420025",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13724970/",
  "id": "6r8qs0rqyb62k",
  "issns": [
    "2050-313X"
  ],
  "landing_url": "https://doi.org/10.1177/2050313x261420025",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "openalex",
      "2747|Renal Transplantation Outcomes and Treatments"
    ]
  ],
  "openalex": "W7213664850",
  "pdf_url": "https://europepmc.org/articles/PMC13724970?pdf=render",
  "pmcid": "PMC13724970",
  "pmid": "42973999",
  "published": "2026-09-19",
  "publisher": "SAGE Publications",
  "ris": "https://research.draconitic.com/paper/6r8qs0rqyb62k.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T12:23:27Z",
      "native_id": "PMC13724970",
      "source": "pmc",
      "url": "https://doi.org/10.1177/2050313x261420025"
    },
    {
      "first_seen": "2026-11-04T15:20:49Z",
      "native_id": "MED:42973999",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42973999"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2747|Renal Transplantation Outcomes and Treatments",
      "subfield": "surgery"
    }
  ],
  "title": "Severe upper gastrointestinal hemorrhage in a renal transplant recipient: A potential complication of immunosuppressive therapy",
  "title_text": "Severe upper gastrointestinal hemorrhage in a renal transplant recipient: A potential complication of immunosuppressive therapy",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:21:20Z",
  "url": "https://research.draconitic.com/paper/6r8qs0rqyb62k",
  "venue": "SAGE Open Medical Case Reports",
  "versions": []
}