{
  "abstract": "Background: Carbapenem-resistant Acinetobacter baumannii (CRAB) infections pose a significant threat to haematopoietic stem cell transplantation (HSCT) recipients. This study characterized CRAB isolates from post-HSCT patients and the ward environment to investigate potential reservoirs of clonal transmission. Presentation of the case: Six HSCT recipients with haematological malignancies were colonized or infected with CRAB. Five patients were identified through throat swab screening, whereas one was detected by urine culture. Of the 42 Acinetobacter baumannii isolates recovered from the HSCT ward environment, 27 (64.3%) were traced to the centralized drinking water supply, including buckets used for cooling and storing boiled water ( N = 2), patients’ drinking water ( N = 13), and water bottles ( N = 12). Whole-genome-based core genome multi-locus sequence typing identified a predominant clonal cluster (cluster A; N = 18) involving A. baumannii isolates from the HSCT ward. This cluster comprised five patient isolates (from five of the six CRAB-positive HSCT recipients) and 13 environmental isolates. Molecular epidemiological analysis revealed that 8 of the 13 environmental isolates (61.5%) originated from the centralized drinking water supply, including one isolate from buckets used for cooling and storing boiled water and seven isolates from patients’ drinking water or water bottles. Conclusion: These findings confirm the circulation of a clonal CRAB strain within the HSCT ward and demonstrate cross-transmission between patients and the environment. Contaminated containers used for storing and transporting drinking water may serve as potential reservoirs for CRAB, facilitating its dissemination within the ward. Strict adherence to standardized potable water management protocols is imperative to prevent CRAB transmission in high-risk units.",
  "abstract_shown": true,
  "affiliations": [
    "The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China; Department of Occupational Health and Environmental Health, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China",
    "The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China",
    "The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China; Corresponding author. The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning 530021, Guangxi, China. Tel.: +86 13877118618; fax: +86 5356594."
  ],
  "article_type": "brief report",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Xiaoyu Luo"
    },
    {
      "affs": [
        1
      ],
      "name": "Yinghua Zhang"
    },
    {
      "affs": [
        1
      ],
      "name": "Shihui Guo"
    },
    {
      "affs": [
        1
      ],
      "name": "Qiaoling Wei"
    },
    {
      "affs": [
        1
      ],
      "name": "Qunxiu Guo"
    },
    {
      "affs": [
        1
      ],
      "name": "Lanlan Li"
    },
    {
      "affs": [
        1
      ],
      "name": "Jingjing Ya"
    },
    {
      "affs": [
        1
      ],
      "name": "Juan Huang"
    },
    {
      "affs": [
        2
      ],
      "name": "Jinai Qin"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6v6cp05hydsqz.bib",
  "cited_by": 0,
  "doi": "10.1016/j.infpip.2026.100601",
  "fulltext_url": "http://www.sciencedirect.com/science/article/pii/S2590088926000958",
  "id": "6v6cp05hydsqz",
  "issns": [
    "2590-0889"
  ],
  "landing_url": "https://doi.org/10.1016/j.infpip.2026.100601",
  "language": "en",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Outbreak Report"
    ],
    [
      "lcc",
      "RA1-1270"
    ],
    [
      "lcc",
      "RC109-216"
    ],
    [
      "openalex",
      "1313|Antibiotic Resistance in Bacteria"
    ]
  ],
  "openalex": "W7214291037",
  "pdf_url": "https://europepmc.org/articles/PMC13718413?pdf=render",
  "pmcid": null,
  "pmid": "42960163",
  "published": "2026-09-25",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/6v6cp05hydsqz.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:44:32Z",
      "native_id": "750d7f0d3159458a825c47d11a892741",
      "source": "doaj",
      "url": "https://doi.org/10.1016/j.infpip.2026.100601"
    },
    {
      "first_seen": "2026-11-01T00:20:52Z",
      "native_id": "MED:42960163",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42960163"
    },
    {
      "first_seen": "2026-11-02T12:22:26Z",
      "native_id": "PMC13718413",
      "source": "pmc",
      "url": "https://doi.org/10.1016/j.infpip.2026.100601"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "lcc:RA1-1270",
      "subfield": "epidemiology-public-health"
    },
    {
      "field": "medicine",
      "origin": "lcc:RC109-216",
      "subfield": "infectious-disease"
    }
  ],
  "title": "Outbreak of carbapenem-resistant",
  "title_text": "Outbreak of carbapenem-resistant",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T12:22:26Z",
  "url": "https://research.draconitic.com/paper/6v6cp05hydsqz",
  "venue": "Infection Prevention in Practice",
  "versions": []
}