{
  "abstract": "Isocitrate dehydrogenase (IDH)-mutant gliomas, including IDH-mutant astrocytomas and IDH-mutant and 1p/19q-codeleted oligodendrogliomas, exhibit biologically distinct behaviors from IDH-wildtype glioblastomas, showing better survival outcomes and requiring different treatment strategies. The recent FDA approval of vorasidenib, an IDH mutation inhibitor, has introduced a paradigm shift in the treatment of IDH-mutant gliomas and has focused attention to the role of imaging information in the routine clinical management of these tumors. In this review, we provide an overview of the clinical fundamentals of IDH-mutant gliomas and highlight the preoperative and postoperative imaging features of these lesions, which are important for radiologists to recognize and communicate with clinicians.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea .",
    "Department of Neurosurgery, Technical University of Munich, Munich, Germany .",
    "Department of Neuroradiology, University Hospital Bonn, Bonn, Germany .",
    "Division for Computational Radiology & Clinical AI (CCIBonn.ai), University Hospital Bonn, Bonn, Germany .",
    "Division for Medical Image Computing (MIC), German Cancer Research Center (DKFZ), Heidelberg, Germany .",
    "Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany .",
    "Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany .",
    "Department of Radiology and Research Institute of Radiological Science and Center for Clinical Imaging Data Science, Yonsei University College of Medicine, Seoul, Republic of Korea .",
    "Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA ."
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Yae Won Park",
      "orcid": "0000-0001-8907-5401"
    },
    {
      "affs": [
        1
      ],
      "name": "Arthur Wagner",
      "orcid": "0000-0001-9947-2240"
    },
    {
      "affs": [
        1
      ],
      "name": "Philipp Karschnia",
      "orcid": "0000-0002-1254-5310"
    },
    {
      "affs": [
        2,
        3,
        4
      ],
      "name": "Philipp Vollmuth",
      "orcid": "0000-0002-6224-0064"
    },
    {
      "affs": [
        5,
        6
      ],
      "name": "Felix Sahm",
      "orcid": "0000-0001-5441-1962"
    },
    {
      "affs": [
        7
      ],
      "name": "Sung Soo Ahn",
      "orcid": "0000-0002-0503-5558"
    },
    {
      "affs": [
        0
      ],
      "name": "Ho Sung Kim",
      "orcid": "0000-0002-9477-7421"
    },
    {
      "affs": [
        8
      ],
      "name": "Ji Eun Park",
      "orcid": "0000-0002-4419-4682"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6vmrbqqehamra.bib",
  "cited_by": 0,
  "doi": "10.3348/kjr.2026.1078",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13744823/",
  "id": "6vmrbqqehamra",
  "issns": [
    "1229-6929",
    "2005-8330"
  ],
  "landing_url": "https://doi.org/10.3348/kjr.2026.1078",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Neuroimaging and Head & Neck"
    ],
    [
      "heading",
      "Review Article"
    ],
    [
      "openalex",
      "2730|Glioma Diagnosis and Treatment"
    ]
  ],
  "openalex": "W7223669668",
  "pdf_url": null,
  "pmcid": "PMC13744823",
  "pmid": "42984200",
  "published": "2026-10-26",
  "publisher": "Korean Society of Radiology",
  "ris": "https://research.draconitic.com/paper/6vmrbqqehamra.ris",
  "sources": [
    {
      "first_seen": "2026-11-11T12:22:18Z",
      "native_id": "PMC13744823",
      "source": "pmc",
      "url": "https://doi.org/10.3348/kjr.2026.1078"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2730|Glioma Diagnosis and Treatment",
      "subfield": "oncology"
    }
  ],
  "title": "Imaging of Isocitrate Dehydrogenase-Mutant Gliomas in the Era of Isocitrate Dehydrogenase Inhibitors: What Radiologists Need to Know",
  "title_text": "Imaging of Isocitrate Dehydrogenase-Mutant Gliomas in the Era of Isocitrate Dehydrogenase Inhibitors: What Radiologists Need to Know",
  "type": "peer-reviewed",
  "updated_at": "2026-11-12T12:21:15Z",
  "url": "https://research.draconitic.com/paper/6vmrbqqehamra",
  "venue": "Korean Journal of Radiology",
  "versions": []
}