{
  "abstract": "New Shamonda virus clades (SHAV-EU1 and SHAV-EU2) emerged in Europe in summer 2026, primarily affecting cattle. We report the first human infection with SHAV-EU1: a French patient with a severely weakened immune system developed fatal encephalitis in September 2026, 1 month after their allogeneic stem cell transplantation. Metatranscriptomics detected SHAV-EU1 in cerebrospinal fluid, confirmed by RT-PCR. Biopsies from central nervous system showed high viral loads. Investigations revealed SHAV-EU1 in serum, respiratory and stool samples at least for 2 months before encephalitis onset.",
  "abstract_shown": true,
  "affiliations": [
    "Anesthésie-Réanimation-Médecine Intensive, Hospices Civils de Lyon, Hôpital Lyon Sud, Pierre Benite, Lyon, France.",
    "Service d'Hématologie clinique, Hospices Civils de Lyon, Hôpital Lyon Sud, Pierre Benite, Lyon, France.",
    "Service de Neurologie, Hospices Civils de Lyon, Hôpital Lyon Sud, Pierre Benite, Lyon, France.",
    "Department of Medical Oncology, Hôpitaux Nord Ouest, Villefranche, France.",
    "Direction Générale de la Santé, Paris, France.",
    "Établissement Français du Sang, La Plaine Saint Denis, France.",
    "Service de Virologie, Plateforme de séquençage Genepii, Centre National de Référence des Virus Respiratoires, Hospices Civils de Lyon, Groupement Hospitalier Nord, Croix-Rousse, Lyon, France.",
    "CIRI, Centre International de Recherche en Infectiologie, Team CARVI, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, France.",
    "Centre International de Recherche en Infectiologie (CIRI), Team GIMAP, Inserm U1111, CNRS UMR5308, ENS de Lyon, Université Claude Bernard - Lyon 1, Université Jean Monnet de Saint-Etienne, Saint-Etienne, France, & Haut Conseil de la Santé Publique, Paris, France.",
    "Department of Infectious Diseases and Tropical Medicine, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.",
    "Université Toulouse, ENVT, INRAE, IHAP, Toulouse, France.",
    "Santé publique France, Lyon/Saint Maurice, France.",
    "Department of Pathology and Neuropathology, Groupe Hospitalier Est, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France; Cancer Research Centre of Lyon (CRCL) INSERM 1052, CNRS 5286, 28 Rue Laennec, 69008 Lyon, France; Faculty of Medicine of Lyon, Université Claude Bernard Lyon 1, Lyon, France.",
    "Centre International de Recherche en Infectiologie (CIRI), Inserm 1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, École Normale Supérieure de Lyon, Univ, Lyon F-69007, France."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 34,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Margot Bonnet"
    },
    {
      "affs": [
        1
      ],
      "name": "Hélène Labussière-Wallet"
    },
    {
      "affs": [
        2
      ],
      "name": "Pauline Dumez"
    },
    {
      "affs": [
        3
      ],
      "name": "Lucie Jauffret"
    },
    {
      "affs": [
        4
      ],
      "name": "Lyderic Aubert"
    },
    {
      "affs": [
        4
      ],
      "name": "Aurélie Avondo-Ray"
    },
    {
      "affs": [
        2
      ],
      "name": "Carole Seurret"
    },
    {
      "affs": [
        2
      ],
      "name": "Perrine Devic"
    },
    {
      "affs": [
        2
      ],
      "name": "Sabrine Souci"
    },
    {
      "affs": [
        5
      ],
      "name": "Syria Laperche"
    },
    {
      "affs": [
        6
      ],
      "name": "Léa Saint Martin"
    },
    {
      "affs": [
        6,
        7
      ],
      "name": "Emilie Frobert"
    },
    {
      "affs": [
        6,
        7
      ],
      "name": "Alexandre Gaymard"
    },
    {
      "affs": [
        6
      ],
      "name": "Jennifer Giorgi"
    },
    {
      "affs": [
        6
      ],
      "name": "Quentin Semanas"
    },
    {
      "affs": [
        6
      ],
      "name": "Richard Chalvignac"
    },
    {
      "affs": [
        6
      ],
      "name": "Antoine Oblette"
    },
    {
      "affs": [
        6
      ],
      "name": "Audrey Lapendry"
    },
    {
      "affs": [
        8
      ],
      "name": "Bruno Pozzetto"
    },
    {
      "affs": [
        9
      ],
      "name": "Thomas Perpoint"
    },
    {
      "affs": [
        10
      ],
      "name": "Mikail Kelleci"
    },
    {
      "affs": [
        10
      ],
      "name": "Aurélie Sécula"
    },
    {
      "affs": [
        10
      ],
      "name": "Charlotte Foret-Lucas"
    },
    {
      "affs": [
        9
      ],
      "name": "Clement Javaux"
    },
    {
      "affs": [
        6,
        7
      ],
      "name": "Florence Morfin"
    },
    {
      "affs": [
        6,
        7
      ],
      "name": "Antonin Bal"
    },
    {
      "affs": [
        11
      ],
      "name": "Elise Brottet"
    },
    {
      "affs": [
        11
      ],
      "name": "Catarina Krug"
    },
    {
      "affs": [
        11
      ],
      "name": "Frederic Jourdain"
    },
    {
      "affs": [
        12
      ],
      "name": "David Meyronet"
    },
    {
      "affs": [
        9,
        13
      ],
      "name": "Florence Ader"
    },
    {
      "affs": [
        10
      ],
      "name": "Jean-Luc Guérin"
    },
    {
      "affs": [
        6,
        7
      ],
      "name": "Laurence Josset"
    },
    {
      "affs": [
        6,
        7
      ],
      "name": "Grégory Destras"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6vsmr8vpgztem.bib",
  "cited_by": 1,
  "doi": "10.2807/1560-7917.es.2026.31.42.2600883",
  "fulltext_url": "https://europepmc.org/articles/PMC13695005",
  "id": "6vsmr8vpgztem",
  "issns": [
    "1025-496X",
    "1560-7917"
  ],
  "landing_url": "https://europepmc.org/article/MED/42921678",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RA1-1270"
    ],
    [
      "openalex",
      "2725|Viral Infections and Vectors"
    ]
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  "openalex": "W7223288683",
  "pdf_url": "https://europepmc.org/articles/PMC13695005?pdf=render",
  "pmcid": "PMC13695005",
  "pmid": "42921678",
  "published": "2026-10-01",
  "publisher": "European Centre for Disease Prevention and Control",
  "ris": "https://research.draconitic.com/paper/6vsmr8vpgztem.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:36Z",
      "native_id": "MED:42921678",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42921678"
    },
    {
      "first_seen": "2026-10-30T13:43:58Z",
      "native_id": "9e88fdf59d09470194f63ba1538fc06c",
      "source": "doaj",
      "url": "https://doi.org/10.2807/1560-7917.es.2026.31.42.2600883"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2725|Viral Infections and Vectors",
      "subfield": "infectious-disease"
    }
  ],
  "title": "Fatal encephalitis caused by Shamonda virus Europe 1 (SHAV-EU1) in a patient with a severely weakened immune system, France, 2026.",
  "title_text": "Fatal encephalitis caused by Shamonda virus Europe 1 (SHAV-EU1) in a patient with a severely weakened immune system, France, 2026.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:43:58Z",
  "url": "https://research.draconitic.com/paper/6vsmr8vpgztem",
  "venue": "Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin",
  "versions": []
}