{
  "abstract": "Fibrosis is a pathological process characterized by excessive deposition of extracellular matrix (ECM), severely impairing organ function. Mesenchymal stem cells (MSCs) have been extensively utilized in the treatment of fibrotic diseases, owing to their distinctive biological characteristics. Nevertheless, challenges persist in the long-term tracking of MSCs and the assessment of therapeutic efficacy during treatment. Non-invasive detection techniques for MSCs during disease therapy, achieved through the synergistic use of magnetic resonance imaging (MRI) and contrast agents, are increasingly mature. This paper outlines the classification, labelling methods, imaging advantages, and comprehensive evaluation of MSCs as MRI molecular probes in fibrotic disease treatment, while exploring their current status and future prospects.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Gulou District, Zhongshan Road 321, Nanjing, 210008, Jiangsu, China.",
    "Department of Radiology, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine, Chinese Academy of Sciences, Hangzhou, 310022, China.",
    "Department of Radiology, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, China.",
    "Clinical Stem Cell Center, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, China.",
    "Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Gulou District, Zhongshan Road 321, Nanjing, 210008, Jiangsu, China. maixl@nju.edu.cn.",
    "Department of Radiology, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, China. maixl@nju.edu.cn."
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Yiqi Pan"
    },
    {
      "affs": [
        2
      ],
      "name": "Yuanyuan Bao"
    },
    {
      "affs": [
        2
      ],
      "name": "Yanbing Bao"
    },
    {
      "affs": [
        2
      ],
      "name": "Mengyi Yang"
    },
    {
      "affs": [
        3
      ],
      "name": "Yuanyuan Xie"
    },
    {
      "affs": [
        4,
        5
      ],
      "name": "Xiaoli Mai",
      "orcid": "0000-0002-2148-6877"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6wwjxfdmdy80w.bib",
  "cited_by": 0,
  "doi": "10.1186/s13287-026-05210-2",
  "fulltext_url": "https://europepmc.org/articles/PMC13729563",
  "id": "6wwjxfdmdy80w",
  "issns": [
    "1757-6512"
  ],
  "landing_url": "https://europepmc.org/article/MED/42972603",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Review"
    ],
    [
      "openalex",
      "2716|Mesenchymal stem cell research"
    ]
  ],
  "openalex": "W7172542392",
  "pdf_url": "https://europepmc.org/articles/PMC13729563?pdf=render",
  "pmcid": "PMC13729563",
  "pmid": "42972603",
  "published": "2026-08-06",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/6wwjxfdmdy80w.ris",
  "sources": [
    {
      "first_seen": "2026-11-04T15:20:44Z",
      "native_id": "MED:42972603",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42972603"
    },
    {
      "first_seen": "2026-11-07T12:22:18Z",
      "native_id": "PMC13729563",
      "source": "pmc",
      "url": "https://doi.org/10.1186/s13287-026-05210-2"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2716|Mesenchymal stem cell research",
      "subfield": "human-genetics"
    }
  ],
  "title": "MRI-based mesenchymal stem cells: a theragnostic approach to fibrosis.",
  "title_text": "MRI-based mesenchymal stem cells: a theragnostic approach to fibrosis.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T12:22:18Z",
  "url": "https://research.draconitic.com/paper/6wwjxfdmdy80w",
  "venue": "Stem cell research & therapy",
  "versions": []
}