{
  "abstract": "Aims: Care home admission often reflects frailty and limited life expectancy, potentially altering the benefit‐harm balance of glucose‐lowering drug (GLD) treatment for type 2 diabetes (T2D). Real‐world data on treatment patterns in this setting remain limited. We examined GLD use for T2D among Danish care home residents.\n\nMaterials and Methods: We conducted a nationwide, population‐based drug utilisation study of all individuals admitted to Danish care homes between 2018 and 2023, using linked national health registries.\n\nResults: Among 88 658 residents (median age: 84 years [IQR: 78–90]; 60% women), 13% (n = 11 101) used GLDs for T2D at admission, with 84% continuing treatment beyond 2 years. Residents using GLDs at admission had long‐standing diabetes (median duration: 12 years [IQR: 6.8–15]), relatively low glycated haemoglobin levels (median: 6.9% [IQR: 6.3–7.8]; 52 mmol/mol [45–62]) with little change around admission, and 43% used more than one GLD class, most commonly metformin (70%) and insulin (36%; basal: 30%; bolus: 16%). Use of glucagon‐like peptide‐1 receptor agonists and sodium‐glucose cotransporter‐2 inhibitors increased over time but remained limited (13% and 24%, respectively, in 2023), despite a high prevalence of cardiorenal disease (84%), and did not differ by cardiorenal disease status. Overall GLD use remained stable around admission, but initiation spiked 3 months before admission (36 initiators/10 000 residents), often following hospitalisation (63%) and primarily involved bolus insulin initiated by hospital physicians.\n\nConclusions: GLD use for T2D among Danish care home residents is high and shows limited deintensification and potential misalignment with guideline recommendations.",
  "abstract_shown": true,
  "affiliations": [
    "Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health University of Southern Denmark Odense Denmark",
    "Hospital Pharmacy Funen Odense University Hospital Odense Denmark",
    "Steno Diabetes Center Odense Odense University Hospital Odense Denmark",
    "Department of Clinical Epidemiology Aarhus University and Aarhus University Hospital Aarhus Denmark",
    "Department of Clinical Research University of Southern Denmark Odense Denmark",
    "Department of Clinical Medicine University of Copenhagen Copenhagen Denmark",
    "Geriatric Research Unit, Department of Clinical Research University of Southern Denmark Odense Denmark",
    "Geriatric Research and Clinical Evidence, Department of Internal Medicine Copenhagen University Hospital Herlev Denmark",
    "Centre for Suicide Research Odense Denmark",
    "Unit of Mental Health Research, Southwest Denmark, Department of Psychiatry Aabenraa Region of Southern Denmark Denmark"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "Hanin Harbi",
      "orcid": "0009-0004-3776-6541"
    },
    {
      "affs": [
        3
      ],
      "name": "Reimar W. Thomsen",
      "orcid": "0000-0001-9135-3474"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Carina Lundby",
      "orcid": "0000-0002-2121-6252"
    },
    {
      "affs": [
        2,
        4
      ],
      "name": "Jacob Volmer Stidsen"
    },
    {
      "affs": [
        2,
        4
      ],
      "name": "Kurt Højlund",
      "orcid": "0000-0002-0891-4224"
    },
    {
      "affs": [
        5,
        6,
        7
      ],
      "name": "Jesper Ryg"
    },
    {
      "affs": [
        0,
        8,
        9
      ],
      "name": "Mette Reilev"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Anton Pottegård",
      "orcid": "0000-0001-9314-5679"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6x3ene91zcpdt.bib",
  "cited_by": 0,
  "doi": "10.1111/dom.71308",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13730979/",
  "id": "6x3ene91zcpdt",
  "issns": [
    "1462-8902",
    "1463-1326"
  ],
  "landing_url": "https://doi.org/10.1111/dom.71308",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Original Article"
    ],
    [
      "openalex",
      "2712|Diabetes Treatment and Management"
    ]
  ],
  "openalex": "W7207839216",
  "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/dom.71308",
  "pmcid": "PMC13730979",
  "pmid": "42687767",
  "published": "2026-09-03",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/6x3ene91zcpdt.ris",
  "sources": [
    {
      "first_seen": "2026-11-08T12:21:16Z",
      "native_id": "PMC13730979",
      "source": "pmc",
      "url": "https://doi.org/10.1111/dom.71308"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2712|Diabetes Treatment and Management",
      "subfield": "endocrinology-metabolism"
    }
  ],
  "title": "Use of Glucose‐Lowering Drugs for Type 2 Diabetes Among Danish Care Home Residents",
  "title_text": "Use of Glucose‐Lowering Drugs for Type 2 Diabetes Among Danish Care Home Residents",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T12:21:16Z",
  "url": "https://research.draconitic.com/paper/6x3ene91zcpdt",
  "venue": "Diabetes, Obesity & Metabolism",
  "versions": []
}