{
  "abstract": "Background\n\nHigh opioid use among individuals with chronic non-cancer pain (CNCP) raises concerns about safe pain management, leading some patients to seek complementary and alternative medicine (CAM). However, treatment-seeking patterns, including how CAM and conventional care are combined, remain unclear among those receiving long-term opioid treatment. The aim was to investigate health-seeking behaviours among individuals with CNCP receiving long-term opioid treatment.Methods\n\nRepeated cross-sectional data from the Danish Health and Morbidity Surveys (2000-2021) were linked to national administrative registers at the individual level. Descriptive statistics and multiple linear and logistic regression models were applied to analyze CAM use, general practitioner (GP) consultations, physiotherapy, and chiropractic care within the last 12 months in relation to CNCP and long-term opioid use.Results\n\nTrends remained largely unchanged from 2000 to 2021, with only minor fluctuations. GP consultations increased with long-term opioid use and were further elevated among individuals with CNCP who also used CAM. Among individuals with CNCP, combined long-term opioid and CAM use was associated with an average of 20.1 additional GP visits (95% CI: 17.5-22.7) compared with individuals without CNCP and no CAM use. Physiotherapy and chiropractic visits were more strongly associated with CAM use than with long-term opioid use. For instance, CNCP individuals using CAM without long-term opioid use had 5.8 times higher odds (95% CI: 4.6-7.4) of at least one chiropractor visit compared with those without CNCP and no CAM use.Conclusion\n\nThese findings highlight distinct health care‑seeking patterns and indicate a substantial health care burden among CNCP individuals receiving long‑term opioid treatment.",
  "abstract_shown": true,
  "affiliations": [
    "National Institute of Public Health, University of Southern Denmark, Studiestraede 6, Copenhagen, 1455, Denmark. hana@sdu.dk.",
    "National Institute of Public Health, University of Southern Denmark, Studiestraede 6, Copenhagen, 1455, Denmark.",
    "Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, Copenhagen, 2200, Denmark.",
    "Pain and Palliative Care Research Group, Multidisciplinary Pain Center, Department of Anaesthesiology, Pain and Respiratory Support, Copenhagen University Hospital - Rigshospitalet, Blegdamsvej 9, dept 7612, Copenhagen, 2100, Denmark.",
    "St. Luke's Academy of Palliative Medicine, St. Luke's Foundation, Bernstorffsvej 20, Hellerup, 2900, Denmark."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Hannah Ahrensberg",
      "orcid": "0009-0000-7247-1213"
    },
    {
      "affs": [
        1
      ],
      "name": "Nanna Gram Ahlmark"
    },
    {
      "affs": [
        1
      ],
      "name": "Susan Andersen"
    },
    {
      "affs": [
        2,
        3,
        4
      ],
      "name": "Geana Paula Kurita"
    },
    {
      "affs": [
        3
      ],
      "name": "Per Føge Jensen"
    },
    {
      "affs": [
        1
      ],
      "name": "Ola Ekholm",
      "orcid": "0000-0002-5563-7098"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/6xfpvns2ewaxj.bib",
  "cited_by": 0,
  "doi": "10.1186/s12906-026-05498-w",
  "fulltext_url": "https://europepmc.org/articles/PMC13688784",
  "id": "6xfpvns2ewaxj",
  "issns": [
    "2662-7671"
  ],
  "landing_url": "https://europepmc.org/article/MED/42907821",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2739|Opioid Use Disorder Treatment"
    ]
  ],
  "openalex": "W7172289000",
  "pdf_url": "https://europepmc.org/articles/PMC13688784?pdf=render",
  "pmcid": "PMC13688784",
  "pmid": "42907821",
  "published": "2026-08-03",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/6xfpvns2ewaxj.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:57Z",
      "native_id": "MED:42907821",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42907821"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2739|Opioid Use Disorder Treatment",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Patterns of complementary and alternative medicine and health care utilization among long-term opioid users with chronic non-cancer pain: a repeated cross-sectional study.",
  "title_text": "Patterns of complementary and alternative medicine and health care utilization among long-term opioid users with chronic non-cancer pain: a repeated cross-sectional study.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:57Z",
  "url": "https://research.draconitic.com/paper/6xfpvns2ewaxj",
  "venue": "BMC complementary medicine and therapies",
  "versions": []
}