{
  "abstract": "We report a mechanochemical copper-catalyzed defluorosilylation of α-trifluoromethyl styrenes with silylboranes. Mechanical activation dramatically accelerated the C–F bond transformation, reducing the reaction time from 8 h to only 30 min at room temperature while substantially decreasing solvent consumption. The reaction exhibits broad substrate compatibility and scalability, highlighting mechanochemistry as an effective strategy for accelerating selective C–F bond functionalization.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Nanopharmaceutical Sciences",
    "Nagoya Institute of Technology, Gokiso",
    "Department of Life Science and Applied Chemistry"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Seishu Ochiai"
    },
    {
      "affs": [
        2,
        1
      ],
      "name": "Daiki Harano"
    },
    {
      "affs": [
        2,
        1
      ],
      "name": "Zhengyu Zhao",
      "orcid": "0009-0005-0933-6461"
    },
    {
      "affs": [
        2,
        1
      ],
      "name": "Norio Shibata"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/705wsk8jcs64k.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15010538/v1",
  "fulltext_url": null,
  "id": "705wsk8jcs64k",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010538/v1",
  "language": null,
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "3003|Fluorine in Organic Chemistry"
    ]
  ],
  "openalex": "W7222003319",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15010538/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-15",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/705wsk8jcs64k.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:24Z",
      "native_id": "10.26434/chemrxiv.15010538",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010538/v2"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:3003|Fluorine in Organic Chemistry",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "Mechanochemically Accelerated Defluorosilylation of α-Trifluoromethyl Styrenes",
  "title_text": "Mechanochemically Accelerated Defluorosilylation of α-Trifluoromethyl Styrenes",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:24Z",
  "url": "https://research.draconitic.com/paper/705wsk8jcs64k",
  "venue": "ChemRxiv",
  "versions": []
}