{
  "abstract": "Cerebral cavernous malformations (CCMs) are low-flow vascular malformations that may be asymptomatic or present with seizures, hemorrhage, headache, or focal neurological deficits. Most are sporadic and solitary, whereas familial CCMs are associated with multiple lesions and autosomal-dominant inheritance. Distinguishing between these forms is clinically relevant for long-term management. We present a 33-year-old woman who presented with generalized tonic-clonic seizures following sleep deprivation. Computed tomography (CT) initially suggested a left frontal intraparenchymal hemorrhage. Magnetic resonance imaging (MRI) subsequently revealed two left frontal Zabramski type II CCMs. Electroencephalography showed cortical dysfunction with paroxysmal activity and contralateral propagation. Antiseizure treatment with phenytoin was initiated and later supplemented with levetiracetam. The patient remained asymptomatic and was referred for tertiary evaluation. This case highlights the diagnostic limitations of CT and the importance of MRI for CCM characterization and detection of multiple lesions. The presence of two cavernomas and a potentially relevant family history raises suspicion for familial CCM, although these findings alone do not establish a hereditary diagnosis. Genetic evaluation and detailed family assessment should therefore be considered. Treatment should be individualized; conservative management is appropriate in selected stable patients, whereas microsurgery and stereotactic radiosurgery are reserved for specific clinical scenarios.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Medicine, National Autonomous University of Mexico, Iztacala Faculty of Higher Studies, Tlalnepantla, MEX.",
    "Department of Neurosurgery, Instituto de Seguridad Social del Estado de México y Municipios (ISSEMYM), Regional Hospital Tlalnepantla, Tlalnepantla, MEX."
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Fernando Uribe-Hernández"
    },
    {
      "affs": [
        1
      ],
      "name": "Jesus Reyes-Reyes"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/725atx4b9cgj1.bib",
  "cited_by": 0,
  "doi": "10.7759/cureus.117023",
  "fulltext_url": "https://europepmc.org/articles/PMC13714666",
  "id": "725atx4b9cgj1",
  "issns": [
    "2168-8184"
  ],
  "landing_url": "https://europepmc.org/article/MED/42953484",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Neurology"
    ],
    [
      "heading",
      "Neurosurgery"
    ],
    [
      "openalex",
      "2728|Vascular Malformations Diagnosis and Treatment"
    ]
  ],
  "openalex": "W7214518858",
  "pdf_url": "https://europepmc.org/articles/PMC13714666?pdf=render",
  "pmcid": "PMC13714666",
  "pmid": "42953484",
  "published": "2026-09-27",
  "publisher": "Cureus Inc.",
  "ris": "https://research.draconitic.com/paper/725atx4b9cgj1.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:41Z",
      "native_id": "MED:42953484",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42953484"
    },
    {
      "first_seen": "2026-11-01T12:22:07Z",
      "native_id": "PMC13714666",
      "source": "pmc",
      "url": "https://doi.org/10.7759/cureus.117023"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "heading:Neurology",
      "subfield": "neurology"
    }
  ],
  "title": "When a Seizure Reveals More Than a Hemorrhage: When to Suspect Cerebral Cavernous Malformations.",
  "title_text": "When a Seizure Reveals More Than a Hemorrhage: When to Suspect Cerebral Cavernous Malformations.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:22:07Z",
  "url": "https://research.draconitic.com/paper/725atx4b9cgj1",
  "venue": "Cureus",
  "versions": []
}