{
  "abstract": "Objective: We aimed to analyze nationwide trends in the diagnosis and management of brain abscess and the associated 6-month mortality in the Republic of Korea between 2005 and 2022.\n\nMethods: We conducted a retrospective nationwide cohort study using data from the National Health Insurance Service database in the Republic of Korea from 2005 to 2022. Patients hospitalized with a primary diagnosis of brain abscess who underwent brain imaging and either lumbar puncture or surgical intervention were included. Patient demographics, treatment modality, and 6-month all-cause mortality trends were analyzed.\n\nResults: Among 8,857 identified patients with brain abscess, 64.5% were male individuals. The mean patient age increased from 49.7 years in 2005 to 60.5 years in 2022, indicating a shift toward an older patient population. Nevertheless, the annual incidence of brain abscesses remained stable at 0.7–1.2 cases per 100,000 people. Regarding surgical management, we observed a decrease in the use of craniotomy and an increase in the use of burr hole drainage over time. The overall 6-month mortality rate was 15.6%, and it did not change significantly during the study period. Mortality was relatively higher in older patients, reaching 36.6% in those aged ≥80 years.\n\nConclusion: Despite an increase in the mean age of patients with brain abscess, both incidence and 6-month mortality rate have remained stable over 18 years. As the population ages, age-adapted management strategies become increasingly important. These findings offer valuable insights for optimizing clinical care and informing health policies on brain abscesses within ageing societies.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Neurosurgery, Uijeongbu Eulji Medical Center, Eulji University College of Medicine, Uijeongbu, Korea .",
    "Department of Neurosurgery, Hanyang University Guri Hospital, Guri, Korea .",
    "Department of Neurosurgery, Nowon Eulji Medical Center, Eulji University College of Medicine, Seoul, Korea ."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Suk Hyun Choi",
      "orcid": "0009-0007-9753-1172"
    },
    {
      "affs": [
        1
      ],
      "name": "Yu Deok Won",
      "orcid": "0000-0002-8822-6631"
    },
    {
      "affs": [
        2
      ],
      "name": "In-Suk Bae",
      "orcid": "0000-0002-0738-9253"
    },
    {
      "affs": [
        0
      ],
      "name": "Yung Ki Park",
      "orcid": "0000-0002-4925-5333"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/72yvh1j7g71qc.bib",
  "cited_by": 0,
  "doi": "10.13004/kjnt.2026.22.e36",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13745177/",
  "id": "72yvh1j7g71qc",
  "issns": [
    "2234-8999",
    "2288-2243"
  ],
  "landing_url": "https://doi.org/10.13004/kjnt.2026.22.e36",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Clinical Article"
    ],
    [
      "openalex",
      "2725|Infectious Diseases and Tuberculosis"
    ]
  ],
  "openalex": "W7221625837",
  "pdf_url": "https://europepmc.org/articles/PMC13745177?pdf=render",
  "pmcid": "PMC13745177",
  "pmid": "43004980",
  "published": "2026-09-10",
  "publisher": "Korean Neurotraumatology Society",
  "ris": "https://research.draconitic.com/paper/72yvh1j7g71qc.ris",
  "sources": [
    {
      "first_seen": "2026-11-11T12:22:46Z",
      "native_id": "PMC13745177",
      "source": "pmc",
      "url": "https://doi.org/10.13004/kjnt.2026.22.e36"
    },
    {
      "first_seen": "2026-11-12T15:22:43Z",
      "native_id": "MED:43004980",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/43004980"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2725|Infectious Diseases and Tuberculosis",
      "subfield": "infectious-disease"
    }
  ],
  "title": "Epidemiological Trends in Brain Abscess Management and Mortality in an Aging Population: A Nationwide Study in the Republic of Korea (2005–2022)",
  "title_text": "Epidemiological Trends in Brain Abscess Management and Mortality in an Aging Population: A Nationwide Study in the Republic of Korea (2005–2022)",
  "type": "peer-reviewed",
  "updated_at": "2026-11-13T03:20:44Z",
  "url": "https://research.draconitic.com/paper/72yvh1j7g71qc",
  "venue": "Korean Journal of Neurotrauma",
  "versions": []
}