{
  "abstract": "OBJECTIVE To estimate the accuracy of rapid tests for Zika and dengue in areas with cocirculation of flaviviruses and their prevalence rates in the municipality of Rio de Janeiro, Brazil, using methodologies for correction of partial verification bias. METHODS A study was conducted based on a seroepidemiological survey. Participants underwent rapid tests for Zika and dengue. Venous blood samples were collected from participants with positive rapid test results for Zika and/or dengue, for diagnostic confirmation by the plaque reduction neutralization test (PRNT). To estimate prevalence, sensitivity and specificity parameters of the rapid tests were verified using the correction methodology proposed by Begg and Greenes (1983). RESULTS A total of 2,120 participants underwent rapid test, and 1,087 (51.2%) were indicated for performing PRNT. The samples from 769 participants underwent PRNT, resulting in 686 (89.2%) positive samples for dengue and 522 (67.8%) for Zika. The sensitivity rates corrected for partial verification bias were 81.0% and 91.5% for the dengue and Zika rapid tests, respectively. The corrected specificity rates were 66.7% for the dengue rapid test and 77.1% for the Zika rapid test. The estimated population prevalence rates, corrected for rapid test accuracy, were 88.0% for dengue (95%CI: 86.7–89.4) and 41.6% for Zika (95%CI: 38.6–44.5). CONCLUSIONS After correction for partial verification bias, the Zika rapid test performed better than the dengue rapid test in the scenario of arbovirus cocirculation. Our findings indicate that the population of the municipality of Rio de Janeiro is predominantly exposed to the dengue virus.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "name": "Geani de Oliveira Marins",
      "orcid": "0000-0002-2280-4128"
    },
    {
      "name": "Thiago de Oliveira Pires",
      "orcid": "0000-0003-4535-5537"
    },
    {
      "name": "Reinaldo Souza-Santos",
      "orcid": "0000-0003-2387-6999"
    },
    {
      "name": "Andréa Sobral",
      "orcid": "0000-0003-0552-771X"
    },
    {
      "name": "Rafael Freitas de Oliveira Franca",
      "orcid": "0000-0002-1846-6007"
    },
    {
      "name": "Elisa de Almeida Neves Azevedo",
      "orcid": "0000-0002-1774-4095"
    },
    {
      "name": "Marília de Albuquerque Sena",
      "orcid": "0000-0003-2802-2140"
    },
    {
      "name": "Raquel de Vasconcellos Carvalhaes de Oliveira",
      "orcid": "0000-0002-8293-8603"
    },
    {
      "name": "André Reynaldo Santos Périssé",
      "orcid": "0000-0002-5253-5774"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/73b5qrg9yjmj1.bib",
  "cited_by": 0,
  "doi": "10.11606/s1518-8787.2026060007181",
  "fulltext_url": "http://www.scielo.br/pdf/rsp/v60/1518-8787-rsp-60-e46.pdf",
  "id": "73b5qrg9yjmj1",
  "issns": [
    "1518-8787",
    "0034-8910"
  ],
  "landing_url": "https://doi.org/10.11606/s1518-8787.2026060007181",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Original Article"
    ],
    [
      "lcc",
      "RA1-1270"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13730518/pdf/?tool=EBI",
  "pmcid": "PMC13730518",
  "pmid": "42987104",
  "published": "2026-11-02",
  "publisher": "Universidade de São Paulo",
  "ris": "https://research.draconitic.com/paper/73b5qrg9yjmj1.ris",
  "sources": [
    {
      "first_seen": "2026-11-03T14:21:30Z",
      "native_id": "1f4dfe8423964d18b9433ad1331153bf",
      "source": "doaj",
      "url": "https://doi.org/10.11606/s1518-8787.2026060007181"
    },
    {
      "first_seen": "2026-11-04T15:20:46Z",
      "native_id": "PMC:PMC13730518",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13730518"
    },
    {
      "first_seen": "2026-11-07T12:23:04Z",
      "native_id": "PMC13730518",
      "source": "pmc",
      "url": "https://doi.org/10.11606/s1518-8787.2026060007181"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "lcc:RA1-1270",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "Estimation of ZIKV and DENV seroprevalence rates in Rio de Janeiro, Brazil, 2018",
  "title_text": "Estimation of ZIKV and DENV seroprevalence rates in Rio de Janeiro, Brazil, 2018",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T12:23:04Z",
  "url": "https://research.draconitic.com/paper/73b5qrg9yjmj1",
  "venue": "Revista de Saúde Pública",
  "versions": []
}