{
  "abstract": "drug-resistant tuberculosis (TB) remains a major public health challenge globally. Monitoring its prevalence and associated factors is essential for effective control strategies. The current study aimed to assess the burden of rifampicin-resistant TB (RR-TB) and its associated factors among patients with TB at Galkayo General Hospital, Puntland, Somalia. a facility-based cross-sectional study was conducted using medical records of patients with TB registered from January 2020 to December 2024. Of 422 randomly reviewed records, 410 with complete data were included in the analysis. Descriptive statistics were used to summarize patient details. Univariate and multivariable logistic regression analyses were used to identify variables associated with RR-TB. Adjusted odds ratios (aOR) with 95% confidence intervals (CIs) were reported. A p-value <.05 was deemed statistically significant. the mean age of participants was 29.9 ± 20.6 years, and 64.6% were male. The prevalence of RR-TB was 9.02% (37/410: 95% CI 6.43%-12.22%). In multivariable logistic analysis, having a history of close contact with a patient with TB (aOR: 2.43, 95% CI 1.13-5.21; P=.02), previous history of TB (aOR: 3.63, 95% CI 1.72-7.67; P<.001), and treatment failure (aOR: 9.03, 95% CI 2.03-40.12; P<.01) were strongly associated with RR-TB. rifampicin-resistant tuberculosis represents a substantial burden among patients with TB in Galkayo General Hospital. Close contact with TB cases, previous TB history, and treatment failure were significant predictors of RR-TB.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Pharmacy, Puntland State University, Puntland, Somalia.",
    "Department of Clinical Pharmacy, School of Pharmacy, College of Health and Medical Science, Haramaya University, Harar, Ethiopia.",
    "Department of Social and Administrative Pharmacy, School of Pharmacy, College of Health and Medical Science, Haramaya University, Harar, Ethiopia.",
    "Department of National Tuberculosis Program, Ministry of Health, Puntland, Somalia.",
    "Department of Epidemiology, School of Public Health, College of Health and Medical Sciences, East Africa University, Qardho, Somalia.",
    "Department of Epidemiology and Biostatistics, School of Public Health, College of Health and Medical Science, Haramaya University, Harar, Ethiopia.",
    "Department of Pharmacology, School of Pharmacy, College of Health and Medical Science, Haramaya University, Harar, Ethiopia."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Hawo Mohamud"
    },
    {
      "affs": [
        1
      ],
      "name": "Kirubel Minsamo Mishore"
    },
    {
      "affs": [
        2
      ],
      "name": "Bisrat Hagos"
    },
    {
      "affs": [
        3
      ],
      "name": "Farah Said Barre"
    },
    {
      "affs": [
        4
      ],
      "name": "Asia Mohammed Ahmed"
    },
    {
      "affs": [
        1
      ],
      "name": "Tewodros Assefa"
    },
    {
      "affs": [
        1
      ],
      "name": "Abera Jambo"
    },
    {
      "affs": [
        5
      ],
      "name": "Assefa Tola"
    },
    {
      "affs": [
        6
      ],
      "name": "Abraham Nigussie Mekuria"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/73j3jxawacmhw.bib",
  "cited_by": 0,
  "doi": "10.11604/pamj.2026.54.34.51751",
  "fulltext_url": "https://europepmc.org/articles/PMC13713750",
  "id": "73j3jxawacmhw",
  "issns": [
    "1937-8688"
  ],
  "landing_url": "https://europepmc.org/article/MED/42953038",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://europepmc.org/articles/PMC13713750?pdf=render",
  "pmcid": "PMC13713750",
  "pmid": "42953038",
  "published": "2026-06-08",
  "publisher": "The Pan African Medical Journal",
  "ris": "https://research.draconitic.com/paper/73j3jxawacmhw.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:41Z",
      "native_id": "MED:42953038",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42953038"
    },
    {
      "first_seen": "2026-10-31T12:24:14Z",
      "native_id": "PMC13713750",
      "source": "pmc",
      "url": "https://doi.org/10.11604/pamj.2026.54.34.51751"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "journal-openalex:F27",
      "subfield": "general"
    }
  ],
  "title": "Prevalence of rifampicin-resistant tuberculosis and its associated factors among patients with tuberculosis at Galkayo General Hospital, Puntland, Somalia: a facility-based cross-sectional study.",
  "title_text": "Prevalence of rifampicin-resistant tuberculosis and its associated factors among patients with tuberculosis at Galkayo General Hospital, Puntland, Somalia: a facility-based cross-sectional study.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:21:22Z",
  "url": "https://research.draconitic.com/paper/73j3jxawacmhw",
  "venue": "The Pan African medical journal",
  "versions": []
}