{
  "abstract": "We report a case of giant hypervascular atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLPS) of the cervicodorsal region in a 62-year-old man. The mass had enlarged slowly over 17 years, with accelerated growth during the preceding 2 years accompanied by a local skin pulling sensation, but without definite airway, neurologic, or major vascular compression. Preoperative computed tomography angiography (CTA) demonstrated a lesion of approximately 20.9 cm × 28.6 cm × 25.4 cm containing internal septa, nodular components, and marked vascularity supplied predominantly by branches of both subclavian arteries. The patient underwent en bloc tumor excision with local advancement flap reconstruction; the resected specimen weighed approximately 6.01 kg, the resulting defect measured approximately 15 cm × 11 cm, the operative time was nearly 6 h, and the estimated blood loss was approximately 700 mL. Postoperative pathology showed focal spindle-cell proliferation with myxoid change and, together with the MDM2, CDK4, and p16 positivity documented in the pathology report, supported the diagnosis of ALT/WDLPS. At short-term follow-up, the incision and flaps had healed well, with no definite local recurrence. This case indicates that a long-standing, slowly enlarging giant lipomatous mass in the cervicodorsal region should not be excluded from the diagnosis of ALT/WDLPS solely on the basis of indolent clinical behavior. When a lesion is very large or imaging suggests rich vascularity, preoperative vascular assessment, hemostatic contingency planning, and simultaneous wound reconstruction design should be incorporated into the surgical plan.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Burns and Plastic Surgery, North Sichuan Medical College, School of Clinical Medicine, Nanchong, Sichuan, China",
    "Department of Burns and Plastic Surgery, West China School of Medicine, Sichuan University, Sichuan University Affiliated Chengdu Second People’s Hospital, Chengdu Second People’s Hospital, Chengdu, Sichuan, China",
    "Department of Medical Cosmetology, West China School of Medicine, Sichuan University, Sichuan University Affiliated Chengdu Second People’s Hospital, Chengdu Second People’s Hospital, Chengdu, Sichuan, China"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Zhonghai Liao"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Feng Qin"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Song Wang"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Xinyu Wan"
    },
    {
      "affs": [
        2
      ],
      "name": "Hong Li"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/757e80q8ynspc.bib",
  "cited_by": 0,
  "doi": "10.3389/fmed.2026.1925841",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13730877/",
  "id": "757e80q8ynspc",
  "issns": [
    "2296-858X"
  ],
  "landing_url": "https://doi.org/10.3389/fmed.2026.1925841",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "openalex",
      "2730|Sarcoma Diagnosis and Treatment"
    ]
  ],
  "openalex": "W7223158773",
  "pdf_url": "https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2026.1925841/pdf",
  "pmcid": "PMC13730877",
  "pmid": "42984546",
  "published": "2026-10-21",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/757e80q8ynspc.ris",
  "sources": [
    {
      "first_seen": "2026-11-07T12:23:51Z",
      "native_id": "PMC13730877",
      "source": "pmc",
      "url": "https://doi.org/10.3389/fmed.2026.1925841"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2730|Sarcoma Diagnosis and Treatment",
      "subfield": "oncology"
    }
  ],
  "title": "Giant hypervascular atypical lipomatous tumor/well-differentiated liposarcoma of the cervicodorsal region: a case report",
  "title_text": "Giant hypervascular atypical lipomatous tumor/well-differentiated liposarcoma of the cervicodorsal region: a case report",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T12:21:11Z",
  "url": "https://research.draconitic.com/paper/757e80q8ynspc",
  "venue": "Frontiers in Medicine",
  "versions": []
}