{
  "abstract": "Background: The reduced and oxidized forms of nicotinamide adenine dinucleotide phosphate (NADPH/NADP) connect cellular reducing power with the glutathione and thioredoxin systems. Peripheral alterations in this network may reflect systemic redox dysregulation in Alzheimer s disease (AD) and mild cognitive impairment (MCI), but the evidence has not been quantitatively synthesized. Objective: To systematically evaluate peripheral blood NADP(H) redox metabolism and related enzymes in AD and MCI and to perform meta analyses when the available data were sufficiently comparable.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Neurology, Guangyuan First People's Hospital"
  ],
  "article_type": "PUBLISHAHEADOFPRINT",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "name": "D. Zhong"
    },
    {
      "name": "D. He"
    },
    {
      "name": "J. Chen"
    },
    {
      "affs": [
        0
      ],
      "name": "c. yangyang"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/75kcpka0najh0.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.11.09.26367672",
  "fulltext_url": "https://www.medrxiv.org/content/10.64898/2026.11.09.26367672v1.full",
  "id": "75kcpka0najh0",
  "issns": [],
  "landing_url": "https://www.medrxiv.org/content/10.64898/2026.11.09.26367672v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "medrxiv",
      "neurology"
    ]
  ],
  "openalex": null,
  "pdf_url": "https://www.medrxiv.org/content/10.64898/2026.11.09.26367672v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-09",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/75kcpka0najh0.ris",
  "sources": [
    {
      "first_seen": "2026-11-11T00:22:23Z",
      "native_id": "10.64898/2026.11.09.26367672",
      "source": "medrxiv",
      "url": "https://www.medrxiv.org/content/10.64898/2026.11.09.26367672v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "medrxiv:neurology",
      "subfield": "neurology"
    }
  ],
  "title": "Peripheral Blood NADP(H) Redox Metabolism in Alzheimers Disease and Mild Cognitive Impairment: A Systematic Review and Meta-analysis Where Feasible",
  "title_text": "Peripheral Blood NADP(H) Redox Metabolism in Alzheimers Disease and Mild Cognitive Impairment: A Systematic Review and Meta-analysis Where Feasible",
  "type": "preprint",
  "updated_at": "2026-11-12T00:20:49Z",
  "url": "https://research.draconitic.com/paper/75kcpka0najh0",
  "venue": "medRxiv",
  "versions": []
}