{
  "abstract": "Introduction\n\nThe DaVinci System is increasingly introduced in many centers worldwide, creating a need for data on surgical outcomes during the early phase of adoption. This study analyzes positive surgical margins (PSMs) and compares outcomes between open, laparoscopic, and robot-assisted radical prostatectomy.Material and methods\n\nWe retrospectively analyzed histopathologic and clinical data from 153, 126, and 721 patients who underwent open, laparoscopic, and robot-assisted radical prostatectomy, respectively. Patients with T2-T3 disease, no lymph node or distant metastases, and no history of neoadjuvant or adjuvant therapy were included. Additionally, surgeon-specific learning curves based on PSM rates were evaluated following the introduction of robot-assisted radical prostatectomy at our institution.Results\n\nPSM were identified in 254 of 721 (35.2%) robot-assisted procedures, predominantly as focal margins, most often located at the apex. PSM rates were comparable between robot-assisted and laparoscopic surgery and higher after open prostatectomy (p = 0.002). PSM distribution was similar between robot-assisted and open approaches, while apical margins were most frequent following laparoscopic prostatectomy. PSMs were associated with a higher risk of early biochemical recurrence in the entire cohort (p = 0.003). Seminal vesicle invasion was consistently associated with early biochemical recurrence across all surgical approaches. Robot-assisted and laparoscopic surgery were associated with a lower risk of early biochemical recurrence than open prostatectomy. Surgeon-specific analysis demonstrated heterogeneous learning curves, with a reduction in PSM rates after the initial 50-100 cases and stabilization with increasing experience.Conclusions\n\nRobot-assisted radical prostatectomy achieved PSM rates comparable to laparoscopic and lower than open prostatectomy during the early phase following its introduction. Despite more adverse pathology, robot-assisted surgery was not associated with an increased early biochemical recurrence, supporting its oncologic safety during adoption. These findings reflect the real-world learning curve associated with the implementation of robotic surgery.",
  "abstract_shown": true,
  "affiliations": [
    "Faculty of Medicine, Bydgoszcz University of Science and Technology, Bydgoszcz, Poland.",
    "Clinical Department of Oncology, Franciszek Łukaszczyk Oncology Center, Bydgoszcz, Poland.",
    "Department of Tumor Pathology and Pathomorphology, Franciszek Łukaszczyk Oncology Centre, Bydgoszcz, Poland.",
    "Doctoral School of Medical and Health Sciences, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.",
    "Department of Obstetrics, Gynecology, and Oncology, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.",
    "Department of Urology, Franciszek Łukaszczyk Oncology Center, Bydgoszcz, Poland.",
    "Department of Oncological Surgery, Nicolaus Copernicus University in Torun, Ludwik Rydygier Collegium Medicum, Bydgoszcz, Poland.",
    "Chair of Pathology, Jan Biziel University Hospital No. 2 in Bydgoszcz, Poland."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Jędrzej Borowczak"
    },
    {
      "affs": [
        0,
        2
      ],
      "name": "Justyna Durślewicz"
    },
    {
      "affs": [
        2,
        3,
        4
      ],
      "name": "Mateusz Maniewski"
    },
    {
      "affs": [
        5
      ],
      "name": "Krzysztof Kamecki"
    },
    {
      "affs": [
        1,
        6
      ],
      "name": "Krzysztof Koper"
    },
    {
      "affs": [
        2,
        4,
        7
      ],
      "name": "Łukasz Szylberg"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/76snbvn7z5dhp.bib",
  "cited_by": 0,
  "doi": "10.5173/ceju.2026.0032",
  "fulltext_url": "https://europepmc.org/articles/PMC13682541",
  "id": "76snbvn7z5dhp",
  "issns": [
    "2080-4806",
    "2080-4873"
  ],
  "landing_url": "https://europepmc.org/article/MED/42903951",
  "language": "eng",
  "licence": "CC-BY-NC-SA",
  "licence_label": "CC BY-NC-SA",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2740|Prostate Cancer Diagnosis and Treatment"
    ]
  ],
  "openalex": "W7204861500",
  "pdf_url": "https://europepmc.org/articles/PMC13682541?pdf=render",
  "pmcid": "PMC13682541",
  "pmid": "42903951",
  "published": "2026-05-15",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/76snbvn7z5dhp.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:59Z",
      "native_id": "MED:42903951",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42903951"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2740|Prostate Cancer Diagnosis and Treatment",
      "subfield": "general"
    }
  ],
  "title": "Surgical margins and biochemical recurrence after the introduction of robot-assisted radical prostatectomy.",
  "title_text": "Surgical margins and biochemical recurrence after the introduction of robot-assisted radical prostatectomy.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:59Z",
  "url": "https://research.draconitic.com/paper/76snbvn7z5dhp",
  "venue": "Central European journal of urology",
  "versions": []
}