{
  "abstract": "Purpose: To evaluate the performance and usability of a commercially available non-woven fabric electrode as a cost-effective and user-friendly alternative to standard corneal contact lens electrodes for recording murine electroretinograms. Methods: Using a paired design, full-field electroretinograms were recorded in the same mice using the commercially available non-woven fabric electrode and a conventional contact lens electrode. Key parameters evaluated included (1) stability of baseline noise, (2) dark-adapted intensity-response curves (0.01-100 cd{middle dot}s{middle dot}m-2), (3) light-adapted intensity-response curves (3-100 cd{middle dot}s{middle dot}m-2), (4) 20-Hz and 30-Hz flicker responses, (5) extended recordings targeting slow c-wave kinetics under dark-adapted conditions, and (6) inter-eye consistency via bilateral simultaneous recordings. Results: Eliminating the need for viscous lubricants, the non-woven fabric electrode simplified placement on the cornea, alignment, and re-application. It yielded a-wave and b-wave amplitudes and peak times comparable or superior to those obtained with standard contact lens electrodes. Notably, during prolonged recordings, the non-woven fabric electrode yielded significantly larger c-wave amplitudes while maintaining equivalent baseline noise stability. Bilateral simultaneous recordings demonstrated high inter-eye correlation and low variability of measurements between contralateral eyes. Conclusions: The non-woven fabric electrode provides high-quality, reproducible electroretinographic recordings comparable to (and for c-waves superior to) those obtained using standard corneal contact lens electrodes. This method facilitates standardized data acquisition and improves inter-laboratory reproducibility of murine electroretinography. Translational Relevance: By reducing financial and technical barriers, this non-woven fabric electrode offers an alternative to specialized recording setups, improving experimental throughput and efficiency in ophthalmic research.",
  "abstract_shown": true,
  "affiliations": [
    "Kawasaki Medical School"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Y. Ishizuka"
    },
    {
      "name": "H. Kamao"
    },
    {
      "name": "J. Matsuda"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/787wqbs16jx33.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.10.07.757191",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.10.07.757191v1.full",
  "id": "787wqbs16jx33",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.10.07.757191v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "neuroscience"
    ],
    [
      "openalex",
      "1312|Retinal Development and Disorders"
    ]
  ],
  "openalex": "W7222196935",
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.10.07.757191v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-07",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/787wqbs16jx33.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:27:54Z",
      "native_id": "10.64898/2026.10.07.757191",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.10.07.757191v5"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "biorxiv:neuroscience",
      "subfield": "neuroscience"
    }
  ],
  "title": "Validation of a Commercially Available Non-Woven Fabric Electrode for Mouse Electroretinography",
  "title_text": "Validation of a Commercially Available Non-Woven Fabric Electrode for Mouse Electroretinography",
  "type": "preprint",
  "updated_at": "2026-10-30T12:29:57Z",
  "url": "https://research.draconitic.com/paper/787wqbs16jx33",
  "venue": "bioRxiv",
  "versions": []
}