{
  "abstract": "AIM: To evaluate the pooled magnitude of retinopathy of prematurity (ROP) among infants’ populations in East Africa. METHODS: A literature search was conducted using PubMed/MEDLINE, Google Scholar, Scopus, and African Journals Online to identify studies from East African published up to August 2025 that reported the magnitude of ROP and its associated factors. The quality of the included cohort and cross-sectional studies was assessed using a modified Newcastle-Ottawa Scale. A random-effects Meta-analysis was used to estimate the pooled magnitude of ROP and adjusted odds ratios (aORs) for associated factors, with results presented using 95% confidence intervals (CI). Heterogeneity among studies was assessed using the I² statistic, and subgroup analysis and meta-regression were performed to explore its sources. Publication bias was assessed using funnel plots and Egger’s regression test. RESULTS: A total of 11 studies were included. The pooled magnitude of ROP in East Africa was 18% (95%CI: 13%–24%, I2=95.77%). The Meta-analysis result showed that infants who received oxygen therapy (pooled OR=4.61, 95%CI: 1.88–7.33), neonates with birth weight less than 1500 g (pooled OR=5.82, 95%CI: 2.89–8.75), and respiratory distress syndrome (pooled OR=3.92, 95%CI: 2.54–5.29) were factors associated with ROP. CONCLUSION: ROP is a significant public health concern in East Africa, affecting nearly one in five preterm infants. Policymakers and healthcare providers should prioritize evidence-based interventions targeting the prevention and early detection of ROP to mitigate its long-term impact on childhood blindness.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Neonatal Nursing, Menelik II Medical and Health Science College, Addis Ababa, P.O. Box 3268, Ethiopia",
    "Public Health Nutrition, Menelik II Medical and Health Science College, Addis Ababa, P.O. Box 3268, Ethiopia",
    "Department of Health Promotion and Health Behavior, School of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, P.O. Box 196, Ethiopia",
    "Department of Pediatric and Child Health Nursing, Menelik II Medical and Health Science College, Addis Ababa, P.O. Box 3268, Ethiopia",
    "Department of Anesthesia, College of Medicine and Health Sciences, University of Gondar, Gondar, P.O. Box 196, Ethiopia",
    "Department of Environmental Health, College of Medicine and Health Science, Injibara University, Injibara, P.O. Box 40, Ethiopia",
    "Department of Health Promotion and Behavioral Science, School of Public Health, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, P.O. Box 79, Ethiopia",
    "Department of Nutrition and Dietetics, Institute of Public Health, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, P.O. Box 79, Ethiopia",
    "Department of Anesthesia, Werabe University College of Medicine and Health Sciences, Werabe, P.O. Box 046, Ethiopia",
    "School of Nursing, College of Health Science and Medicine, Wolaita Sodo University, Sodo, P.O. Box 138, Ethiopia",
    "Department of Public Health, College of Health Sciences, Salale University, Fiche, P.O. Box 245, Ethiopia",
    "Office of Research Innovation and Commercialization, Khyber Medical University, Hayatabad, Peshawar 25100, Pakistan",
    "Department of Emergency and Critical Care Nurse, Menelik II Medical and Health Science College, Addis Ababa, P.O. Box 3268, Ethiopia",
    "Department of Public Health, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, P.O. Box 21, Ethiopia",
    "Department of Public Health, Menelik II Medical and Health Science College, Addis Ababa, P.O. Box 3268, Ethiopia",
    "Department of Anesthesia, College of Medicine and Health Sciences, Wachemo University, Hossana, P.O. Box 667, Ethiopia",
    "Department of Surgical Nursing, Menelik II Medical and Health Science College, School of Nursing and Midwifery, Addis Ababa, P.O. Box 3268, Ethiopia"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 21,
  "authors": [
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        0
      ],
      "name": "Yohannes Godie Ashebir"
    },
    {
      "affs": [
        1
      ],
      "name": "Olyad Kuma Getahun"
    },
    {
      "affs": [
        2
      ],
      "name": "Gebeyehu Lakew"
    },
    {
      "affs": [
        3
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      "name": "Mathewos Mekonnen Gemmechu"
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      "name": "Mulualem Endeshaw Zeleke"
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      "name": "Yibeltal Assefa Atalay"
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    {
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      "name": "Amlaku Nigusie Yirsaw"
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    {
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        6
      ],
      "name": "Eyob Ketema Bogale"
    },
    {
      "affs": [
        7
      ],
      "name": "Abiy Hailu Tikuneh"
    },
    {
      "affs": [
        8
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      "name": "Abas Ali Hassen"
    },
    {
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      ],
      "name": "Eyasu Alem Lake"
    },
    {
      "affs": [
        10
      ],
      "name": "Tadesse Nigussie"
    },
    {
      "affs": [
        11
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      "name": "Bushra Bibi"
    },
    {
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        12
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      "name": "Fikiru Yigezu Jaleta"
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    {
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      "name": "Abebe Gedefaw Belete"
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    {
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      "name": "Genanew Kassie Getahun"
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      "name": "Kedir Seid"
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      "name": "Chala Getaneh Jaleta"
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    {
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      "name": "Sintayehu Samuel Lorato"
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    {
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        15
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      "name": "Mitiku Desalegn"
    },
    {
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        16
      ],
      "name": "Dawit Tesfaye Rundasa"
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  "bibtex": "https://research.draconitic.com/paper/78ctpj17mvseh.bib",
  "cited_by": 0,
  "doi": "10.18240/ijo.2026.11.18",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13717371/",
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  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
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  "native_subjects": [
    [
      "heading",
      "Meta-Analysis"
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      "2741|Retinopathy of Prematurity Studies"
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  "pmcid": "PMC13717371",
  "pmid": "42959660",
  "published": "2026-11-02",
  "publisher": "Press of International Journal of Ophthalmology",
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  "subjects": [
    {
      "field": "medicine",
      "origin": "heading:Meta-Analysis",
      "subfield": "clinical-trials"
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  "title": "Retinopathy of prematurity among infants in East Africa: a systematic review and Meta-analysis",
  "title_text": "Retinopathy of prematurity among infants in East Africa: a systematic review and Meta-analysis",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T12:21:42Z",
  "url": "https://research.draconitic.com/paper/78ctpj17mvseh",
  "venue": "International Journal of Ophthalmology",
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