{
  "abstract": "Background/Aims: Aeromonas species are Gram-negative, flagellated bacilli suggested to be associated with inflammatory bowel disease (IBD) flare-ups, but their precise role remains controversial. This retrospective study investigated Aeromonas as an enteropathogen in patients with IBD.\n\nMethods: This study analyzed patients who tested positive for Aeromonas via stool multiplex PCR at Kangdong Sacred Heart Hospital between June 2023 and May 2025.\n\nResults: Among the overall IBD cohort, Aeromonas was detected in 11/94 patients (11.7%; five with ulcerative colitis and six with Crohn's disease), identifying it as the second most prevalent pathogen, closely following Clostridioides difficile (14.9%, 14/94). This positivity rate was significantly higher than the 3.6% (111/3,056) observed in patients without IBD (p<0.001). IBD patients showed significantly lower PCR cycle threshold values (34.68±4.5 vs. 39.24±4.5, p=0.004), indicating a higher abundance of genetic material.\n\nConclusions: In conclusion, Aeromonas positivity is significantly more prevalent in IBD patients and is associated with a higher abundance of genetic material and inflammatory markers. Nevertheless, it is unclear if Aeromonas, acting as an enteropathogen, directly triggers acute flare-ups or is merely a consequence of a pre-existing compromised mucosal environment in patients with IBD.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea",
    "Department of Laboratory, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Daein Kim"
    },
    {
      "affs": [
        0
      ],
      "name": "Jiyoung Yoon"
    },
    {
      "affs": [
        1
      ],
      "name": "Jae-seok Kim"
    },
    {
      "affs": [
        0
      ],
      "name": "You Sun Kim",
      "orcid": "0000-0002-5156-3458"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7b8nsz3nwdhtg.bib",
  "cited_by": 0,
  "doi": "10.4166/kjg.2027.027",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13714424/",
  "id": "7b8nsz3nwdhtg",
  "issns": [
    "1598-9992",
    "2233-6869"
  ],
  "landing_url": "https://doi.org/10.4166/kjg.2027.027",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Lower GI Tract"
    ],
    [
      "heading",
      "ORIGINAL ARTICLE"
    ],
    [
      "openalex",
      "1311|Inflammatory Bowel Disease"
    ]
  ],
  "openalex": "W7223573993",
  "pdf_url": "https://www.kjg.or.kr/journal/download_pdf.php?doi=10.4166/kjg.2027.027",
  "pmcid": "PMC13714424",
  "pmid": "42928008",
  "published": "2026-10-25",
  "publisher": "Korean Society of Gastroenterology",
  "ris": "https://research.draconitic.com/paper/7b8nsz3nwdhtg.ris",
  "sources": [
    {
      "first_seen": "2026-11-01T12:21:55Z",
      "native_id": "PMC13714424",
      "source": "pmc",
      "url": "https://doi.org/10.4166/kjg.2027.027"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1311|Inflammatory Bowel Disease",
      "subfield": "genetics-genomics"
    }
  ],
  "title": "The Role of Aeromonas Species as Enteropathogens in Patients with Inflammatory Bowel Disease",
  "title_text": "The Role of Aeromonas Species as Enteropathogens in Patients with Inflammatory Bowel Disease",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:21:55Z",
  "url": "https://research.draconitic.com/paper/7b8nsz3nwdhtg",
  "venue": "The Korean Journal of Gastroenterology",
  "versions": []
}