{
  "abstract": "Purpose\n\nTo evaluate the association of surgical quality and survival in patients with advanced ovarian cancer in a real-world setting.Methods\n\nThis population-based registry study analysed FIGO stage III/IV ovarian cancer patients in Hamburg, Germany (2014-2024). Patients were categorized by surgical outcome (no macroscopic residuals vs. macroscopic residuals). Kaplan-Meier functions and Cox proportional hazards models estimated associations with survival outcomes.Results\n\nThe cohort comprised 576 patients (median age 65 years, median follow-up 57 months). No macroscopic residuals were achieved in 370 patients (64.2%). In multivariable analysis, no macroscopic residuals were associated with reduced mortality risk (HR 0.62, 95% CI: 0.42-0.90) and reduced progression risk (HR 0.68, 95% CI: 0.49-0.94). Advanced FIGO stage, poor performance status, and increasing age were independent predictors of worse outcomes.Conclusion\n\nAchieving no macroscopic residuals remains a critical prognostic factor in advanced ovarian cancer. The rate of 64.2% demonstrates that optimal surgical outcomes are achievable in routine practice, though opportunities for improvement remain compared to specialized centres.",
  "abstract_shown": true,
  "affiliations": [
    "Hamburg Cancer Registry, Hamburg, Germany. annemarie.schultz@bwfg.hamburg.de.",
    "Hamburg Cancer Registry, Hamburg, Germany.",
    "Department of Gynaecology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.",
    "Department of Gynaecology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany. b.schmalfeldt@uke.de."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Schultz Annemarie",
      "orcid": "0009-0005-4378-5885"
    },
    {
      "affs": [
        1
      ],
      "name": "Peters Frederik"
    },
    {
      "affs": [
        2
      ],
      "name": "Jaeger Anna"
    },
    {
      "affs": [
        3
      ],
      "name": "Schmalfeldt Barbara"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7g23cw2k5s6e1.bib",
  "cited_by": 0,
  "doi": "10.1007/s00404-026-08578-x",
  "fulltext_url": "https://europepmc.org/articles/PMC13719812",
  "id": "7g23cw2k5s6e1",
  "issns": [
    "0932-0067",
    "1432-0711"
  ],
  "landing_url": "https://europepmc.org/article/MED/42957917",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research"
    ],
    [
      "openalex",
      "2743|Ovarian cancer diagnosis and treatment"
    ]
  ],
  "openalex": "W7224511983",
  "pdf_url": "https://europepmc.org/articles/PMC13719812?pdf=render",
  "pmcid": "PMC13719812",
  "pmid": "42957917",
  "published": "2026-10-29",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/7g23cw2k5s6e1.ris",
  "sources": [
    {
      "first_seen": "2026-11-01T00:20:36Z",
      "native_id": "MED:42957917",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42957917"
    },
    {
      "first_seen": "2026-11-02T12:23:42Z",
      "native_id": "PMC13719812",
      "source": "pmc",
      "url": "https://doi.org/10.1007/s00404-026-08578-x"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2743|Ovarian cancer diagnosis and treatment",
      "subfield": "reproductive-child"
    }
  ],
  "title": "Surgical quality and long-term outcomes in advanced ovarian cancer: a population based registry study from Hamburg, Germany 2014-2024.",
  "title_text": "Surgical quality and long-term outcomes in advanced ovarian cancer: a population based registry study from Hamburg, Germany 2014-2024.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:20:48Z",
  "url": "https://research.draconitic.com/paper/7g23cw2k5s6e1",
  "venue": "Archives of gynecology and obstetrics",
  "versions": []
}