{
  "abstract": "Introduction: Mandibular advancement devices (MADs) are used for obstructive sleep apnea (OSA), but the frequency of new-device fabrication following breakage during treatment is uncertain.\n\nMethods: We analyzed 219 patients treated with a custom-made fixed-type MAD at a single center. The endpoint was the first documented new-device fabrication due to device breakage, across successive appliances if necessary, measured from the initial recorded fabrication date. The record term “repair” denoted new-device fabrication, whereas adjustment of an existing device was not an event. Dental-treatment and loss-related replacements did not end patient-level observation. For patients without a documented breakage event, absence of a return visit was assumed to mean no recorded event through March 31, 2025.\n\nResults: Fifty-eight of 219 patients (26.5%) had a first breakage-related remanufacture; 161 were administratively censored. Two patients had an intervening new device for a non-device reason: one later had a breakage event and one did not. Median analytic observation time was 45.9 months (IQR 18.4-77.3; range 0.3-180.7). Estimated event-free survival at one and three years was 91.6% (95% CI 87.0-94.6) and 81.1% (95% CI 74.8-86.0), respectively. Actual last-contact dates and loss to clinical follow-up could not be determined.\n\nConclusion: Breakage-related new-device fabrication was documented during MAD treatment. These patient-level estimates depend on an unverified assumption that patients who did not return had no recorded event; they do not describe the physical lifespan of a single appliance or treatment efficacy.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Oral and Maxillofacial Surgery, Kanazawa Medical University, Uchinada, JPN",
    "Department of Physical and Cognitive Rehabilitation Technology, Kanazawa Medical University Hospital, Uchinada, JPN",
    "Department of Pathology Ⅱ, Kanazawa Medical University, Uchinada, JPN"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Shintaro Kakuda"
    },
    {
      "affs": [
        0
      ],
      "name": "Shuto Ito"
    },
    {
      "affs": [
        0
      ],
      "name": "Yasuhisa Sawai"
    },
    {
      "affs": [
        0
      ],
      "name": "Yota Yamauchi"
    },
    {
      "affs": [
        1
      ],
      "name": "Fukunori Toukai"
    },
    {
      "affs": [
        0
      ],
      "name": "Satoshi Wada"
    },
    {
      "affs": [
        2
      ],
      "name": "Takanobu Takata"
    },
    {
      "affs": [
        0
      ],
      "name": "Eiji Mitate"
    },
    {
      "affs": [
        0
      ],
      "name": "Hiroyuki Nakano"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7hxmdpw6p60n6.bib",
  "cited_by": 0,
  "doi": "10.7759/cureus.117448",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13731442/",
  "id": "7hxmdpw6p60n6",
  "issns": [
    "2168-8184"
  ],
  "landing_url": "https://doi.org/10.7759/cureus.117448",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Dentistry"
    ],
    [
      "openalex",
      "2737|Obstructive Sleep Apnea Research"
    ]
  ],
  "openalex": "W7219857836",
  "pdf_url": "https://www.cureus.com/articles/534443-breakage-related-remanufacture-of-mandibular-advancement-devices-in-patients-with-obstructive-sleep-apnea-a-retrospective-study-of-219-patients.pdf",
  "pmcid": "PMC13731442",
  "pmid": "42984975",
  "published": "2026-10-04",
  "publisher": "Cureus Inc.",
  "ris": "https://research.draconitic.com/paper/7hxmdpw6p60n6.ris",
  "sources": [
    {
      "first_seen": "2026-11-08T12:21:38Z",
      "native_id": "PMC13731442",
      "source": "pmc",
      "url": "https://doi.org/10.7759/cureus.117448"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2737|Obstructive Sleep Apnea Research",
      "subfield": "physiology"
    }
  ],
  "title": "Breakage-Related Remanufacture of Mandibular Advancement Devices in Patients With Obstructive Sleep Apnea: A Retrospective Study of 219 Patients",
  "title_text": "Breakage-Related Remanufacture of Mandibular Advancement Devices in Patients With Obstructive Sleep Apnea: A Retrospective Study of 219 Patients",
  "type": "peer-reviewed",
  "updated_at": "2026-11-08T12:21:38Z",
  "url": "https://research.draconitic.com/paper/7hxmdpw6p60n6",
  "venue": "Cureus",
  "versions": []
}