{
  "abstract": null,
  "abstract_shown": false,
  "affiliations": [],
  "article_type": "Article",
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "name": "Rong Wang"
    },
    {
      "name": "Yan Zhang"
    },
    {
      "name": "Hexiang Li"
    },
    {
      "name": "Nana Liu"
    },
    {
      "name": "Shengxiang Li"
    },
    {
      "name": "Daxu Li"
    },
    {
      "name": "Bingnan Ren"
    },
    {
      "name": "Feng Ye"
    },
    {
      "name": "Meiju Ji"
    },
    {
      "name": "Peng Hou"
    },
    {
      "name": "Qi Yang",
      "orcid": "0000-0002-3443-8997"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7j2sf3dvwkpm1.bib",
  "cited_by": 0,
  "doi": "10.1016/j.isci.2026.118080",
  "fulltext_url": null,
  "id": "7j2sf3dvwkpm1",
  "issns": [
    "2589-0042"
  ],
  "landing_url": "https://www.cell.com/iscience/fulltext/S2589-0042(26)03463-2",
  "language": null,
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "http://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Cancer"
    ],
    [
      "heading",
      "Cell biology"
    ],
    [
      "heading",
      "Human metabolism"
    ],
    [
      "heading",
      "Molecular biology"
    ]
  ],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-29",
  "publisher": "Elsevier BV",
  "ris": "https://research.draconitic.com/paper/7j2sf3dvwkpm1.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:16Z",
      "native_id": "10.1016/j.isci.2026.118080",
      "source": "feed-cell",
      "url": "https://www.cell.com/iscience/fulltext/S2589-0042(26)03463-2"
    },
    {
      "first_seen": "2026-10-30T12:17:49Z",
      "native_id": "10.1016/j.isci.2026.118080",
      "source": "crossref",
      "url": "https://linkinghub.elsevier.com/retrieve/pii/S2589004226034632"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "heading:Molecular biology",
      "subfield": "molecular-biology"
    },
    {
      "field": "biology",
      "origin": "heading:Cell biology",
      "subfield": "cell-biology"
    },
    {
      "field": "medicine",
      "origin": "heading:Cancer",
      "subfield": "oncology"
    }
  ],
  "title": "MEK blockade exhausts the transcriptional reserve of lipid modifications and sensitizes mutant HRAS to statins",
  "title_text": "MEK blockade exhausts the transcriptional reserve of lipid modifications and sensitizes mutant HRAS to statins",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T12:20:54Z",
  "url": "https://research.draconitic.com/paper/7j2sf3dvwkpm1",
  "venue": "iScience",
  "versions": []
}