{
  "abstract": "Purpose\n\nTo evaluate the ability of anatomical nephrometry scoring systems to predict malignant histology in patients undergoing surgery for small renal masses (SRMs) ≤ 4 cm.Materials and methods\n\nSeventy-two patients with SRMs treated between January 2015 and March 2024 were retrospectively analyzed. Preoperative imaging was used to calculate eight nephrometry scoring systems: RENAL, PADUA, SPARE, DAP, ABC, C-index, NePhRO, Renal Pelvic Score and Zhongshan. Receiver operating characteristic (ROC) curve analyses were performed to assess the diagnostic performance of each scoring system for predicting malignant histology. Associations between nephrometry scores and malignant histology were evaluated using univariable and multivariable logistic regression analyses.Results\n\nBenign pathology was observed in 30.6% of patients. In univariable analyses, PADUA (p = 0.003), RENAL (p = 0.002), SPARE (p = 0.010), DAP (p = 0.012), ABC (p = 0.011), and Zhongshan (p = 0.044) scores were significantly associated with malignant histology. The C-index demonstrated the highest diagnostic performance (AUC = 0.850, p < 0.001). In multivariable analysis, the C-index remained the only independent predictor of malignancy (OR = 0.490, 95% CI 0.246-0.974, p = 0.042). Higher C-index values were associated with benign tumors, whereas lower values were associated with clear-cell renal cell carcinoma.Conclusion\n\nAnatomical nephrometry scores, particularly the C-index, may serve as practical preoperative indicators of tumor biology in SRMs. Incorporating the C-index into clinical evaluation may improve risk stratification and potentially help reduce unnecessary surgical treatment for benign lesions after further validation.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Urology, Kütahya Health Science University, Kütahya, Turkey.",
    "Department of Urology, Kütahya Health Science University, Kütahya, Turkey. ibrahimguvenkartal@gmail.com.",
    "Department of Urology, İzmir Bakırçay University, İzmir, Turkey. ibrahimguvenkartal@gmail.com.",
    "Department of Radiology, Kütahya Health Science University, Kütahya, Turkey.",
    "Department of Urology, Health Science University, Konya City Hospital, Konya, Turkey."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Mustafa Baturay Çetinkaya"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "İbrahim Kartal",
      "orcid": "0000-0002-2313-3522"
    },
    {
      "affs": [
        0
      ],
      "name": "Okan Alkış"
    },
    {
      "affs": [
        3
      ],
      "name": "Şahinde Atlanoğlu"
    },
    {
      "affs": [
        0
      ],
      "name": "Halil İbrahim İvelik"
    },
    {
      "affs": [
        0
      ],
      "name": "Şeref Çoşer"
    },
    {
      "affs": [
        0,
        4
      ],
      "name": "Mehmet Sevim"
    },
    {
      "affs": [
        0
      ],
      "name": "Bekir Aras"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7m71cg6ydee8r.bib",
  "cited_by": 0,
  "doi": "10.1186/s12894-026-02291-2",
  "fulltext_url": "https://europepmc.org/articles/PMC13721603",
  "id": "7m71cg6ydee8r",
  "issns": [
    "1471-2490"
  ],
  "landing_url": "https://europepmc.org/article/MED/42958163",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research"
    ],
    [
      "openalex",
      "2740|Renal cell carcinoma treatment"
    ]
  ],
  "openalex": "W7172232041",
  "pdf_url": "https://europepmc.org/articles/PMC13721603?pdf=render",
  "pmcid": "PMC13721603",
  "pmid": "42958163",
  "published": "2026-08-03",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/7m71cg6ydee8r.ris",
  "sources": [
    {
      "first_seen": "2026-11-01T00:20:47Z",
      "native_id": "MED:42958163",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42958163"
    },
    {
      "first_seen": "2026-11-03T12:22:16Z",
      "native_id": "PMC13721603",
      "source": "pmc",
      "url": "https://doi.org/10.1186/s12894-026-02291-2"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2740|Renal cell carcinoma treatment",
      "subfield": "general"
    }
  ],
  "title": "Predicting malignant histology in small renal masses: the role of anatomical and radiological nephrometry scores.",
  "title_text": "Predicting malignant histology in small renal masses: the role of anatomical and radiological nephrometry scores.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:22:16Z",
  "url": "https://research.draconitic.com/paper/7m71cg6ydee8r",
  "venue": "BMC urology",
  "versions": []
}