{
  "abstract": "Objectives: Post-radiotherapy tissue changes in laryngeal cancer can hinder accurate imaging assessment of recurrence and tumour extent. We compared pre-operative magnetic resonance imaging staging performance in recurrent laryngeal cancer versus primary laryngeal cancer.\n\nMethods: Retrospective single-centre study of 51 total laryngectomy patients (2012–2021). Magnetic resonance imaging assessments of invasion/extension were compared with histopathology (reference standard) to compute accuracy, sensitivity and specificity.\n\nResults: Magnetic resonance imaging accuracy differed between groups. In the recurrent laryngeal cancer group, accuracy was highest for lymph node metastasis (88.5 per cent) and extra-laryngeal spread (76.9 per cent), whereas it was lowest for cartilage invasion (53.9 per cent) and paraglottic involvement (57.8 per cent). In the primary laryngeal cancer group, magnetic resonance imaging performed best for subglottic and supraglottic extension (76.0 per cent each) and cartilage invasion (72.0 per cent), but showed limited accuracy for extra-laryngeal spread (36.0 per cent) and lymph node metastasis (60.0 per cent).\n\nConclusion: Magnetic resonance imaging tended to overestimate tumour extent in both groups. It was sensitive overall, but less specific in certain subsites, particularly the paraglottic region. Negative nodal findings may be reassuring, although conclusions regarding nodal status remain limited.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Otorhinolaryngology/ Head and Neck Surgery, Faculty of Medicine, Gazi University, Ankara, Türkiye",
    "Department of Radiology, Faculty of Medicine, Gazi University, Ankara, Türkiye",
    "Department of Medical Pathology, Faculty of Medicine, Gazi University, Ankara, Türkiye"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Süleyman Cebeci"
    },
    {
      "affs": [
        0
      ],
      "name": "Emirhan Akyol",
      "orcid": "0000-0001-9233-6123"
    },
    {
      "affs": [
        1
      ],
      "name": "Murat Uçar"
    },
    {
      "affs": [
        2
      ],
      "name": "Mehmet Arda İnan"
    },
    {
      "affs": [
        1
      ],
      "name": "M.Mehmet İncesu"
    },
    {
      "affs": [
        2
      ],
      "name": "Ilayda Kılıç"
    },
    {
      "affs": [
        0
      ],
      "name": "Mehmet Düzlü"
    },
    {
      "affs": [
        0
      ],
      "name": "Utku Aydil"
    },
    {
      "affs": [
        0
      ],
      "name": "Muammer Melih Şahin"
    },
    {
      "affs": [
        0
      ],
      "name": "Recep Karamert"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7mk4yhpt6w1hz.bib",
  "cited_by": 0,
  "doi": "10.1017/s0022215126105052",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13719256/",
  "id": "7mk4yhpt6w1hz",
  "issns": [
    "0022-2151",
    "1748-5460"
  ],
  "landing_url": "https://doi.org/10.1017/s0022215126105052",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Main Article"
    ],
    [
      "openalex",
      "2733|Head and Neck Cancer Studies"
    ]
  ],
  "openalex": "W7163080540",
  "pdf_url": null,
  "pmcid": "PMC13719256",
  "pmid": "42219924",
  "published": "2026-10-30",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/7mk4yhpt6w1hz.ris",
  "sources": [
    {
      "first_seen": "2026-11-02T12:23:07Z",
      "native_id": "PMC13719256",
      "source": "pmc",
      "url": "https://doi.org/10.1017/s0022215126105052"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2733|Head and Neck Cancer Studies",
      "subfield": "general"
    }
  ],
  "title": "Diagnostic accuracy of magnetic resonance imaging for post-radiotherapy recurrent laryngeal cancer: a comparison study with primary laryngeal cancer",
  "title_text": "Diagnostic accuracy of magnetic resonance imaging for post-radiotherapy recurrent laryngeal cancer: a comparison study with primary laryngeal cancer",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T12:23:07Z",
  "url": "https://research.draconitic.com/paper/7mk4yhpt6w1hz",
  "venue": "The Journal of Laryngology and Otology",
  "versions": []
}