{
  "abstract": "The formation of biomolecular condensates has been linked to a broad range of essential cellular processes, including immune signaling cascades, mRNA transport, and autophagy. Conversely, phase-separated condensates have also been associated with aberrant protein misfolding and subsequent aggregation in neurodegenerative disease-related processes. Protein phase separation and phase transitions involve the formation of heterogeneous and dynamic assemblies that can evolve into gel-like or semi-crystalline states, which are challenging to characterize using high-resolution structural biology techniques. Solid-state nuclear magnetic resonance (NMR) spectroscopy now offers a broad arsenal of methods to probe the structural and dynamic features of viscous condensates, elastic solids, coacervates and rigid protein assemblies. This review provides an overview of solid-state NMR approaches that are readily applicable and discusses potential methodological developments to investigate protein condensates and coacervates as well as to study protein phase separation and phase transitions.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "name": "Seamoon Deb"
    },
    {
      "name": "Erick Dufourc"
    },
    {
      "name": "Birgit Habenstein"
    },
    {
      "name": "Sven Saupe"
    },
    {
      "name": "Antoine Loquet"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7mpzdj0vvvn0v.bib",
  "cited_by": 0,
  "doi": "10.1016/j.bpc.2026.107692",
  "fulltext_url": null,
  "id": "7mpzdj0vvvn0v",
  "issns": [
    "0301-4622"
  ],
  "landing_url": "https://hal.science/hal-05842104v1",
  "language": "en",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.chim"
    ],
    [
      "hal",
      "0.sdv"
    ],
    [
      "openalex",
      "1607|Advanced NMR Techniques and Applications"
    ]
  ],
  "openalex": "W7171488353",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-28",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/7mpzdj0vvvn0v.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:02Z",
      "native_id": "hal-05842104",
      "source": "hal",
      "url": "https://hal.science/hal-05842104v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1607|Advanced NMR Techniques and Applications",
      "subfield": "physical"
    }
  ],
  "title": "Solid-state NMR methods to investigate biomolecular condensates, protein phase transition, phase separation and coacervates",
  "title_text": "Solid-state NMR methods to investigate biomolecular condensates, protein phase transition, phase separation and coacervates",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:02Z",
  "url": "https://research.draconitic.com/paper/7mpzdj0vvvn0v",
  "venue": "Biophysical Chemistry",
  "versions": []
}