{
  "abstract": "Post-HTP1.6 updated edition of the Theory of Everything Research Programme synthesis paper. The previously published Post-TP1 edition is preserved and followed by an addendum incorporating the prospective HTP1.6 matched-control adjudication. The original TP1-A result remains supported: causal self-maintenance emerged in all 40 preregistered artificial CRN populations. HTP1.6 then tested whether that external disturbance-recovery phenotype uniquely required the evolved catalytic architecture. Of 40 new targets, 21 obtained adequately matched non-catalytic expanded-passive controls and all 21 reproduced the held-out functional profile (bypass proportion 1.000; Wilson 95% CI approximately 0.845-1.000). The dependency map is therefore refined into TP1-A1 (causal self-maintenance emergence: SUPPORTED), TP1-A2 (catalytic architectural uniqueness/necessity: NOT SUPPORTED), and TP1-P (physical/protocellular transport: OPEN). TP2, TP3, TP4 and OP1 retain their previous statuses.",
  "abstract_shown": true,
  "affiliations": [
    "Independent Researcher"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 1,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Kenneth Craggs",
      "orcid": "0009-0003-2075-3771"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7n4a0srr7mxj5.bib",
  "cited_by": 0,
  "doi": "10.5281/zenodo.23644651",
  "fulltext_url": null,
  "id": "7n4a0srr7mxj5",
  "issns": [],
  "landing_url": "https://zenodo.org/records/23644651",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [],
  "openalex": null,
  "pdf_url": "https://zenodo.org/api/records/23644651/files/From_Candidate_Hierarchy_to_Experimental_Dependency_Map_Post_HTP1_6_Updated_Edition.pdf/content",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-25",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/7n4a0srr7mxj5.ris",
  "sources": [
    {
      "first_seen": "2026-11-08T12:21:05Z",
      "native_id": "23644651",
      "source": "zenodo",
      "url": "https://zenodo.org/records/23644651"
    }
  ],
  "subjects": [],
  "title": "From Candidate Hierarchy to Experimental Dependency Map: Post-HTP1.6 Updated Edition.",
  "title_text": "From Candidate Hierarchy to Experimental Dependency Map: Post-HTP1.6 Updated Edition.",
  "type": "preprint",
  "updated_at": "2026-11-08T12:21:05Z",
  "url": "https://research.draconitic.com/paper/7n4a0srr7mxj5",
  "venue": "Zenodo",
  "versions": []
}