{
  "abstract": "We characterized the intestinal microbiota of Misgurnus anguillicaudatus using 16S rRNA gene sequencing (V4 region). Strains secreting extracellular digestive enzymes were functionally screened, identified by 16S rRNA sequencing, and evaluated for biosafety. Microbial diversity analysis revealed that the intestinal microbiota of M. anguillicaudatus was dominated by the genera Vibrio, Pseudoalteromonas, and Aeromonas as core predominant taxa. Functional screening yielded four strains. Three non-hemolytic strains secreting amylase, lipase, and protease were identified as Aeromonas hydrophila, Shewanella xiamenensis, and Cedecea neteri, respectively. A. veronii was excluded due to its β-hemolytic activity. Biosafety assessment indicated that all three strains exhibited satisfactory biosafety. The three strains, A. hydrophila, S. xiamenensis, and C. neteri, obtained in this study possess potential probiotic functions in aiding host digestion and promoting nutrient absorption, and provide candidate strains for the development of microecological preparations for aquatic animals.",
  "abstract_shown": true,
  "affiliations": [
    "School of Life Science, Liaoning Normal University, Dalian 116029, China",
    "Key Laboratory of Loach Genetics and Breeding of Jiangsu Province, Soochow University, Suzhou 215123, China",
    "School of Basic Medical Sciences, Suzhou Medical College of Soochow University, Suzhou 215123, China"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Zhaoxin Sui",
      "orcid": "0009-0003-4421-7658"
    },
    {
      "affs": [
        0
      ],
      "name": "Mingshuai Shu"
    },
    {
      "affs": [
        0
      ],
      "name": "Ruining Zhang",
      "orcid": "0009-0006-8707-1574"
    },
    {
      "affs": [
        0
      ],
      "name": "Jianing Yu",
      "orcid": "0009-0005-6980-6605"
    },
    {
      "affs": [
        0
      ],
      "name": "Zhuo Dai"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Yi Sun"
    },
    {
      "affs": [
        0
      ],
      "name": "Jun Li",
      "orcid": "0000-0003-2845-7566"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7pbwtwd4d5b8x.bib",
  "cited_by": 0,
  "doi": "10.3390/ijms27209097",
  "fulltext_url": "https://europepmc.org/articles/PMC13705447",
  "id": "7pbwtwd4d5b8x",
  "issns": [
    "1422-0067"
  ],
  "landing_url": "https://www.mdpi.com/1422-0067/27/20/9097",
  "language": "eng",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2403|Aquaculture disease management and microbiota"
    ]
  ],
  "openalex": "W7168088417",
  "pdf_url": "https://europepmc.org/articles/PMC13705447?pdf=render",
  "pmcid": "PMC13705447",
  "pmid": "42941867",
  "published": "2026-10-14",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/7pbwtwd4d5b8x.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:55Z",
      "native_id": "10.3390/ijms27209097",
      "source": "crossref",
      "url": "https://www.mdpi.com/1422-0067/27/20/9097"
    },
    {
      "first_seen": "2026-10-30T12:22:12Z",
      "native_id": "MED:42941867",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42941867"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:2403|Aquaculture disease management and microbiota",
      "subfield": "immunology"
    }
  ],
  "title": "The Screening and Identification of Potential Probiotics in Misgurnus anguillicaudatus Intestine",
  "title_text": "The Screening and Identification of Potential Probiotics in Misgurnus anguillicaudatus Intestine",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:22:12Z",
  "url": "https://research.draconitic.com/paper/7pbwtwd4d5b8x",
  "venue": "International Journal of Molecular Sciences",
  "versions": []
}