{
  "abstract": "To describe the epidemiology, treatment patterns, overall survival (OS) and healthcare resource use among patients with warm autoimmune haemolytic anaemia (wAIHA) in Taiwan, adult patients with ≥1 diagnosis code for autoimmune haemolytic anaemia (AIHA) with record of wAIHA‐related treatments between 2017 and 2022 were retrospectively identified from Taiwan's National Health Insurance Research Database linked with the National Death Registry and Taiwan Cancer Registry. The wAIHA incidence was 1.27 per 100 000 person‐years, and the 2022 prevalence was 4.58 per 100 000 persons. Corticosteroid monotherapy was the most common treatment across all lines, with 30.2% of patients remaining on corticosteroids 2 years after diagnosis. Blood transfusions were common in the first year following diagnosis, with 52.5% of patients receiving at least one emergency transfusion. The 5‐year OS probability, estimated using Kaplan–Meier analysis, was 67.1%. The median annualised medical cost was NT$ (New Taiwan dollar) 106 464 (interquartile range [IQR]: 49 088–285 856) or US$ (US dollar) 3327 (IQR: 1534–8933). Intensive care unit admissions were the primary cost driver (adjusted exponentiated coefficient: 2.76 [95% confidence interval: 2.26–3.36]), determined using a generalised linear model with a gamma distribution and log link function. Overall, significant unmet medical needs remain for wAIHA management in Taiwan, including addressing prolonged reliance on corticosteroids, sub‐optimal OS outcomes and high medical service use.",
  "abstract_shown": true,
  "affiliations": [
    "Division of Hematology‐Oncology, Department of Internal Medicine Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan",
    "Research Services Center for Health Information Chang Gung University Taoyuan Taiwan",
    "Johnson & Johnson Singapore Singapore Singapore",
    "Johnson & Johnson Horsham Pennsylvania USA",
    "Johnson & Johnson Titusville New Jersey USA",
    "Saw Swee Hock School of Public Health National University of Singapore Singapore Singapore",
    "School of Pharmacy, Faculty of Health & Medical Sciences Taylor's University Malaysia Subang Jaya Malaysia",
    "Department of Artificial Intelligence Chang Gung University Taoyuan Taiwan",
    "Institute of Health Data Science Chang Gung University Taoyuan Taiwan",
    "Department of Biomedical Science Chang Gung University Taoyuan Taiwan"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Hsiao‐Wen Kao"
    },
    {
      "affs": [
        1
      ],
      "name": "Shu‐Chen Chang",
      "orcid": "0000-0002-5064-714X"
    },
    {
      "affs": [
        2
      ],
      "name": "Dae Young Yu",
      "orcid": "0000-0003-1091-5792"
    },
    {
      "affs": [
        1
      ],
      "name": "Tse‐Chih Chou",
      "orcid": "0009-0001-2739-9264"
    },
    {
      "affs": [
        2
      ],
      "name": "I‐Ching Tsai",
      "orcid": "0009-0003-4831-5474"
    },
    {
      "affs": [
        3
      ],
      "name": "Ann Leon",
      "orcid": "0009-0004-1310-7277"
    },
    {
      "affs": [
        4
      ],
      "name": "Alexis Krumme",
      "orcid": "0000-0001-9633-861X"
    },
    {
      "affs": [
        2,
        5,
        6
      ],
      "name": "David Bin‐Chia Wu"
    },
    {
      "affs": [
        1,
        7,
        8,
        9
      ],
      "name": "Chee Jen Chang",
      "orcid": "0000-0002-7725-7555"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/7pt0dmvg5n2k6.bib",
  "cited_by": 0,
  "doi": "10.1111/bjh.70792",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13748348/",
  "id": "7pt0dmvg5n2k6",
  "issns": [
    "0007-1048",
    "1365-2141"
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  "landing_url": "https://doi.org/10.1111/bjh.70792",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "ORIGINAL PAPER"
    ],
    [
      "heading",
      "Original Paper"
    ],
    [
      "heading",
      "Red Cells and Iron"
    ],
    [
      "openalex",
      "2720|Blood groups and transfusion"
    ]
  ],
  "openalex": "W7220411705",
  "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bjh.70792",
  "pmcid": "PMC13748348",
  "pmid": "42833886",
  "published": "2026-10-05",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/7pt0dmvg5n2k6.ris",
  "sources": [
    {
      "first_seen": "2026-11-13T12:26:12Z",
      "native_id": "PMC13748348",
      "source": "pmc",
      "url": "https://doi.org/10.1111/bjh.70792"
    }
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  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2720|Blood groups and transfusion",
      "subfield": "general"
    }
  ],
  "title": "Warm autoimmune haemolytic anaemia in Taiwan: A population‐based study of epidemiology, treatment patterns, survival and healthcare utilisation (2017–2022)",
  "title_text": "Warm autoimmune haemolytic anaemia in Taiwan: A population‐based study of epidemiology, treatment patterns, survival and healthcare utilisation (2017–2022)",
  "type": "peer-reviewed",
  "updated_at": "2026-11-13T12:26:12Z",
  "url": "https://research.draconitic.com/paper/7pt0dmvg5n2k6",
  "venue": "British Journal of Haematology",
  "versions": []
}